Clinical trial: effects of tegaserod on gastric motor and sensory function in patients with functional dyspepsia.

Author: FriedM, FruehaufH, SalterJ, StutzB, ThumshirnM, TougasG

Paper Details 
Original Abstract of the Article :
BACKGROUND Tegaserod, a serotonin receptor type-4 partial agonist, stimulates gastrointestinal motility and has been shown to increase gastric volumes before and after a meal in healthy volunteers. Its effect on gastric motor and sensory function in patients with functional dyspepsia is unclear. AIM...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2007.03521.x

データ提供:米国国立医学図書館(NLM)

Tegaserod: A Potential New Ally in the Treatment of Functional Dyspepsia

Functional dyspepsia, a common gastrointestinal disorder, can significantly impact quality of life. This research explores the effects of tegaserod, a serotonin receptor type-4 partial agonist, on gastric motor and sensory function in patients with functional dyspepsia.

The study found that tegaserod significantly increased postprandial gastric compliance in patients with functional dyspepsia. This suggests that tegaserod may improve gastric motility and alleviate symptoms associated with this disorder. The study also observed that tegaserod had no effect on gastric sensation, highlighting its potential to specifically target motor function without altering sensory perception.

Tegaserod: A Promising Therapeutic Agent for Functional Dyspepsia

The study's findings indicate that tegaserod may be a valuable therapeutic agent for functional dyspepsia. Its ability to enhance gastric compliance suggests that it could improve gastric emptying and alleviate symptoms such as bloating and fullness.

Improving Gastric Function and Quality of Life: The Potential of Tegaserod

Functional dyspepsia can significantly impact daily life, and effective treatments are crucial. Tegaserod's ability to improve gastric motor function without affecting sensory perception offers a promising approach to manage this disorder, potentially enhancing quality of life for patients.

Dr. Camel's Conclusion

This research, like a camel carrying a precious cargo through the desert, has unearthed a new and potentially effective treatment for functional dyspepsia. Tegaserod's ability to improve gastric compliance offers a beacon of hope for patients seeking relief from this debilitating disorder. This discovery could lead to better management of functional dyspepsia, enhancing the well-being of those affected.

Date :
  1. Date Completed 2008-03-31
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

17892526

DOI: Digital Object Identifier

10.1111/j.1365-2036.2007.03521.x

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English

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