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Ocular side effects in chronic myeloid leukemia patients treated with imatinib.

Author: AlimenaGiuliana, BrecciaMassimo, CannellaLaura, CarmosinoIda, FrustaciAnnamaria, GentiliniFabiana, LatagliataRoberto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Imatinib mesylate, a tyrosine kinase inhibitor, is used to treat chronic myeloid leukemia (CML). This report describes the ocular complications observed in imatinib-treated Ph+ CML patients, ranging from mild periorbital edema to serious adverse events such as glaucoma.
Paper Details　
Original Abstract of the Article :
Imatinib mesylate is a selective inhibitor of the bcr/abl, c-kit and PDGF receptor tyrosine kinases. Its ocular toxicity is little known with mild periorbital oedema being the most commonly reported side effect. We here describe our experience on ocular complications in imatinib treated Ph+ CML pati...See full text at original site
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引用元：
https://doi.org/10.1016/j.leukres.2007.10.016

データ提供：米国国立医学図書館（NLM）

Imatinib and the Eye: A Camel's View of Ocular Side Effects

The world of cancer treatment is vast and complex, with countless medications vying for a place in the therapeutic arsenal. This research explores the ocular side effects of imatinib, a drug used to treat chronic myeloid leukemia (CML). Like a camel navigating a treacherous sandstorm, patients taking imatinib can encounter a range of ocular complications, from mild to severe.

The study found that imatinib can cause a variety of ocular side effects, ranging from periorbital edema (swelling around the eyes) to serious conditions like glaucoma. It's like a desert oasis that promises relief, but sometimes throws a curveball in the form of unexpected challenges.

Navigating the Desert of Ocular Side Effects

The findings highlight the importance of careful monitoring for potential ocular side effects in patients taking imatinib. Early detection and intervention are crucial to prevent long-term complications. It's like having a trusty camel guide, keeping a watchful eye out for any signs of trouble.

A Camel's Advice for CML Patients

If you're receiving treatment for CML, be sure to discuss any changes in your vision with your doctor. It's like checking for cracks in the oasis's walls, ensuring a safe and healthy journey through treatment.

Dr. Camel's Conclusion

Like a camel traversing a desert, patients taking imatinib need to be aware of the potential ocular side effects. This research sheds light on the importance of careful monitoring and timely intervention. It's a reminder that even in the oasis of treatment, vigilance is crucial.

Date :
  1. Date Completed 2008-08-05
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

18061664

DOI: Digital Object Identifier

10.1016/j.leukres.2007.10.016

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Article Analysis
・Side Effects of imatinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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