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Baseline nail disease in patients with moderate to severe psoriasis and response to treatment with infliximab during 1 year.

Author: GriffithsChristopher E M, GuzzoCynthia, HsuMing-Chun, LiShu, NestleFrank O, ReichKristian, RichPhoebe, ScherRichard K, XuStephen

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Infliximab was found to be effective in treating nail psoriasis.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Although nail psoriasis occurs frequently in patients with psoriatic skin lesions, effective treatments are limited. OBJECTIVE: Occurrence of nail psoriasis by type and incidence of nail clearance using the Nail Psoriasis Severity Index were evaluated. METHODS: This was a 50-week, phas...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaad.2007.07.042

データ提供：米国国立医学図書館（NLM）

Nail Psoriasis: A Desert Storm in the Body

Psoriasis, like a fierce sandstorm, can wreak havoc on the skin, leaving behind a trail of scaly patches and discomfort. This study investigates the effectiveness of infliximab in treating nail psoriasis, a condition that can significantly impact quality of life. Imagine a group of travelers, seeking relief from the relentless heat of nail psoriasis, finding solace in the oasis of infliximab.

Infliximab: A Potential Oasis for Nail Psoriasis

The study found that infliximab significantly improved nail psoriasis in patients with moderate to severe psoriasis. This is a remarkable finding, offering hope for patients struggling with this debilitating condition. The study found that infliximab was particularly effective in clearing nail pitting and onycholysis, two of the most common nail abnormalities associated with psoriasis.

Navigating the Desert of Psoriasis Treatment

This study highlights the potential of infliximab in treating nail psoriasis. It reinforces the importance of considering the unique challenges faced by patients with this condition. As researchers, we continue to explore the vast desert of psoriasis, seeking to discover new treatments and improve the lives of those affected by this chronic disease.

Dr.Camel's Conclusion

This study provides encouraging evidence for the effectiveness of infliximab in treating nail psoriasis. While further research is needed to fully understand its long-term impact, this study offers a beacon of hope for patients struggling with this challenging condition. We, as researchers, continue our journey through the desert of psoriasis, seeking to discover new treatments and improve the lives of those affected by this debilitating disease.

Date :
  1. Date Completed 2008-02-08
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18083272

DOI: Digital Object Identifier

10.1016/j.jaad.2007.07.042

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Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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