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An update on the safety and tolerability of pimecrolimus cream 1%: evidence from clinical trials and post-marketing surveillance.
Author: CorkMichael J, LangleyRichard G B, LugerThomas A, PaulCarle, SchneiderDirk
Original Abstract of the Article :
In this report, we review the data on the safety and tolerability of pimecrolimus cream 1% (Elidel) from clinical trials and post-marketing surveillance in patients with atopic dermatitis. These data demonstrate that topically applied pimecrolimus is minimally absorbed through the skin and has a fav...See full text at original site
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000102118
データ提供:米国国立医学図書館(NLM)
Assessing the Safety and Tolerability of Pimecrolimus Cream 1%
This research explores the [dermatology] and [immunology] of pimecrolimus cream 1%, a topical medication used to treat atopic dermatitis. The study reviewed data from [clinical trials and post-marketing surveillance] to evaluate the safety and tolerability of this treatment. The results demonstrated that [pimecrolimus cream 1% is generally safe and well-tolerated], with minimal absorption through the skin. The most common side effects were [temporary skin reactions, particularly burning]. However, the study found that [pimecrolimus cream 1% increased the risk of herpes simplex virus infections in children], prompting further investigation.
Evaluating the Safety of Pimecrolimus
The study's findings indicate that [pimecrolimus cream 1% is generally safe and effective for treating atopic dermatitis]. The authors emphasize that [while the risk of herpes simplex virus infections is higher in children, pimecrolimus cream 1% is still considered safe].
Navigating the Desert of Skin Conditions
Just as a camel can endure the harsh desert environment, our skin is our first line of defense against a variety of challenges. Understanding the delicate balance of our skin's immune system is crucial for managing conditions like atopic dermatitis.
Dr.Camel's Conclusion
This research highlights the importance of balancing the benefits and risks of medications. While pimecrolimus cream 1% offers relief for atopic dermatitis, the study's findings remind us to be cautious about its use, especially in children.
Date :
- Date Completed 2008-03-11
- Date Revised 2014-11-20
Further Info :
Related Literature
English
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