Linezolid-induced reversible bicytopenia in a 4-year-old boy with methicillin-resistant Staphylococcus aureus bacteremia.

Author: BalciYasemin Isik, CeyhanMehmet, SecmeerGulten, TavilBetul, TavilYusuf, TuncerMurat, YildirimInci

Paper Details 
Original Abstract of the Article :
The authors report on a 4-year-old child with the diagnosis of tetralogy of Fallot (TOF) and infective endocarditis. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated from the blood culture of the patient. While receiving imipenem, amikacin, and linezolid therapies, the boy's general c...See full text at original site
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引用元:
https://doi.org/10.1080/08880010701703628

データ提供:米国国立医学図書館(NLM)

Linezolid-Induced Reversible Bicytopenia: A Case Study

This case study presents a report of a 4-year-old boy with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia who experienced reversible bicytopenia (a decrease in both red blood cells and platelets) while receiving linezolid therapy. The boy's condition improved after receiving imipenem, amikacin, and linezolid, but his hemoglobin and platelet count progressively decreased during linezolid treatment. Following discontinuation of linezolid, the boy's hemoglobin and platelet count gradually recovered. The case highlights the potential of linezolid to induce cytopenias in children and emphasizes the importance of monitoring blood counts during linezolid therapy. Early recognition of this side effect can prevent unnecessary investigations and allow for timely intervention.

Understanding the Potential Side Effects of Linezolid

This case study serves as a valuable reminder of the potential side effects associated with linezolid, particularly in children. The findings underscore the importance of close monitoring of blood counts during linezolid therapy to ensure early detection and prompt management of any adverse effects. This study, like a cautionary signpost in the desert, highlights the importance of vigilance and timely interventions in patient care.

Linezolid: A Powerful Antibiotic with Potential Side Effects

Linezolid is a valuable antibiotic used to treat serious infections, but it can have potential side effects, including cytopenias. This case study, like a treasure map leading through the complexities of medication side effects, emphasizes the importance of monitoring blood counts during linezolid therapy to ensure patient safety. Understanding the nuances of medication effects, much like understanding the delicate balance of a desert ecosystem, requires constant observation and vigilance.

Dr.Camel's Conclusion

The world of medicine, like the vast and unpredictable desert, holds both wonders and potential dangers. This case study, like a cautionary tale whispered by the desert winds, highlights the importance of monitoring medication side effects. It reminds us that while antibiotics are powerful tools in combating infections, they can also have unforeseen consequences. Vigilance and careful observation are crucial in ensuring patient safety and navigating the complexities of medical treatment.

Date :
  1. Date Completed 2008-04-07
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18231956

DOI: Digital Object Identifier

10.1080/08880010701703628

Related Literature

SNS
PICO Info
in preparation
Languages

English

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