Aminophylline reversal of prolonged postoperative sedation induced by propofol.

Author: FukudaKenichi, FukunagaAtsuo, IchinoheTatsuya, KanekoYuzuru, KasaharaMasataka, SakuraiSatoru

Paper Details 
Original Abstract of the Article :
Propofol is frequently used for intravenous sedation or anesthesia in ambulatory and office-based anesthesia. Although awakening is usually rapid, there are instances of delayed recovery from propofol anesthesia. It has been reported that aminophylline antagonizes the sedative effects of several ane...See full text at original site
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引用元:
https://doi.org/10.1007/s00540-007-0587-x

データ提供:米国国立医学図書館(NLM)

Aminophylline Reversal of Prolonged Postoperative Sedation Induced by Propofol

This study explores a potential solution to the sometimes-troublesome delayed recovery from propofol anesthesia. Propofol is a popular anesthetic used for short procedures, but occasionally, patients experience prolonged sedation. The study investigated the use of aminophylline as a potential antidote for this situation. The researchers reported that intravenous aminophylline effectively reversed prolonged propofol-induced sedation in several patients. Interestingly, no side effects or delayed re-sedation were observed following aminophylline administration.

Potential Propofol Antagonist

The results suggest that aminophylline could be a useful tool for reversing prolonged propofol sedation, potentially improving patient recovery after surgery. The fact that no side effects were reported is particularly encouraging.

Health and Lifestyle Implications

While this study presents promising results, it's important to remember that it was based on case reports. Further research is needed to confirm the effectiveness and safety of aminophylline in a larger population. However, this study offers a potential solution for a challenging post-operative scenario, which could improve patient recovery and reduce the risk of complications.

Dr.Camel's Conclusion

Think of propofol as a soothing sandstorm that can sometimes linger a bit too long. Aminophylline, like a refreshing desert oasis, may help clear the fog of prolonged sedation. This is exciting news for patients, especially those who experience delayed recovery after surgery. However, like any oasis, it's crucial to approach this potential solution with a healthy dose of caution and await further research to confirm its effectiveness and safety.

Date :
  1. Date Completed 2008-05-14
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18306023

DOI: Digital Object Identifier

10.1007/s00540-007-0587-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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