Jet lag: therapeutic use of melatonin and possible application of melatonin analogs.

Author: CardinaliDaniel P, Pandi-PerumalSeithikurippu R, SpenceD Warren, SrinivasanVenkataramanujan, TrakhtIlya

Paper Details 
Original Abstract of the Article :
Each year millions of travelers undertake long distance flights over one or more continents. These multiple time zone flights produce a constellation of symptoms known as jet lag. Familiar to almost every intercontinental traveler is the experience of fatigue upon arrival in a new time zone, but alm...See full text at original site
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引用元:
https://doi.org/10.1016/j.tmaid.2007.12.002

データ提供:米国国立医学図書館(NLM)

Melatonin: A Sleep-Aid for Jet Lag and Beyond

Jet lag, the disruption of your body's natural sleep-wake cycle due to long-distance travel across time zones, is a common traveler's woe. This study delves into the use of melatonin, a hormone naturally produced by the body, as a potential treatment for jet lag and other circadian rhythm disorders.

The researchers highlight the role of melatonin in regulating the circadian rhythm, a 24-hour cycle that governs sleep-wake patterns, hormone secretion, and other bodily functions. Melatonin has been shown to be effective in resetting disrupted circadian rhythms and promoting sleep in jet lag and other conditions, such as delayed sleep phase syndrome and shift-work disorder.

Melatonin's effectiveness in treating jet lag is attributed to its action on melatonin receptors in the suprachiasmatic nucleus, the brain's master clock. It can be particularly helpful for flights across less than 7-8 time zones. However, for longer journeys, pre-departure melatonin administration is recommended to prevent the symptoms of jet lag.

Melatonin: A Natural Solution for Disrupted Sleep

This study underscores the potential of melatonin as a safe and effective treatment for jet lag and other circadian rhythm disorders. The research suggests that melatonin can be a valuable tool for travelers seeking to minimize the disruptive effects of crossing time zones. Melatonin, a natural sleep-inducing hormone, can help to alleviate the uncomfortable symptoms of jet lag, promoting a smoother transition to a new time zone and ensuring a more restful sleep.

Navigating Time Zones: A Natural Remedy

Think of jet lag like a desert wanderer who's lost their way. Their internal compass is disrupted, and they're disoriented and exhausted. Melatonin, like a guide star, can help to realign their internal clock, restoring a sense of balance and enabling them to find their way back to a regular sleep pattern. This study provides evidence that melatonin can be a valuable tool for travelers seeking a natural solution for jet lag.

Dr.Camel's Conclusion

Melatonin is a natural and effective sleep aid that can be used to treat jet lag and other circadian rhythm disorders. It's like a gentle breeze carrying the scent of a desert flower, calming the mind and promoting a restful night's sleep. Melatonin can help travelers to navigate the challenges of time zone changes, ensuring a more comfortable and restorative sleep experience.

Date :
  1. Date Completed 2008-06-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18342269

DOI: Digital Object Identifier

10.1016/j.tmaid.2007.12.002

SNS
PICO Info
in preparation
Languages

English

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