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Formulation and biopharmaceutical evaluation of transdermal patch containing benztropine.
Author: ChiSang-Cheol, HaiNguyen Thien, KimJuyoung, ParkEun-Seok
Original Abstract of the Article :
Benztropine (BZ) is a potent muscarinic receptor antagonist that has been used for the treatment of Parkinson disease. However, the oral administration of BZ is often limited because of its many dose-related side effects. In this study, BZ was formulated into drug-in adhesive (DIA) patches in an att...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.ijpharm.2008.01.024
データ提供:米国国立医学図書館(NLM)
Transdermal Benztropine Patches: A New Approach to Parkinson's Disease Treatment
Imagine Parkinson's disease as a desert landscape, where movement becomes increasingly difficult, like traversing a sandy terrain. This research explores a new approach to treating Parkinson's disease, using transdermal patches to deliver benztropine, a medication that helps alleviate symptoms.
The researchers developed transdermal patches containing benztropine, aiming to improve the delivery and effectiveness of this medication. They found that these patches effectively delivered benztropine to the skin, resulting in a significant bioavailability compared to oral administration. This research offers a promising new avenue for delivering benztropine, potentially offering improved treatment outcomes for those living with Parkinson's disease.
Transdermal Delivery: A New Frontier for Parkinson's Treatment
This research highlights the potential of transdermal drug delivery for treating Parkinson's disease. It suggests that this approach could offer several benefits, including improved patient compliance, reduced side effects, and potentially more effective treatment outcomes.
Understanding Parkinson's Disease
If you are living with Parkinson's disease, it's essential to consult with your healthcare provider to discuss the best treatment options for you. They can help you understand the different approaches available, including medication, therapy, and lifestyle modifications, and develop a personalized plan to manage your condition effectively.
Dr.Camel's Conclusion
This research showcases the innovative spirit of medical research, exploring new ways to deliver medications and improve treatment outcomes for individuals living with chronic conditions. It's a reminder that the quest for better healthcare solutions continues, driven by the dedication of scientists and healthcare professionals to enhance patient well-being.
Date :
- Date Completed 2008-08-25
- Date Revised 2016-11-24
Further Info :
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