Paper Details

  1. Home
  2. Paper Details

Adenosine A(2A) receptors in Parkinson's disease treatment.

Author: CieślakMarek, KomoszyńskiMichał, WojtczakAndrzej

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Adenosine A(2A) receptor antagonists are showing promise in the treatment of Parkinson's disease. These drugs may improve mobility and reduce side effects when used in combination with other Parkinson's medications.
Paper Details　
Original Abstract of the Article :
Latest results on the action of adenosine A(2A) receptor antagonists indicate their potential therapeutic usefulness in the treatment of Parkinson's disease. Basal ganglia possess high levels of adenosine A(2A) receptors, mainly on the external surfaces of neurons located at the indirect tracts betw...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583202/

データ提供：米国国立医学図書館（NLM）

Adenosine A2A Receptors: A New Target for Parkinson's Disease Treatment

This research explores the potential of adenosine A2A receptor antagonists as a novel treatment for Parkinson's disease, a debilitating neurological disorder. The study investigates the role of adenosine A2A receptors in the brain, particularly in the basal ganglia, a region involved in movement control.

Adenosine A2A Receptors and Parkinson's Disease

The researchers found that adenosine A2A receptors are highly concentrated in the basal ganglia and play a crucial role in regulating movement. They also discovered that blocking adenosine A2A receptors, particularly in combination with dopamine agonists, can improve motor function in patients with Parkinson's disease.

A New Approach to Managing Parkinson's Disease

This research offers a new approach to managing Parkinson's disease by targeting adenosine A2A receptors. Like a camel navigating a desert, researchers are always seeking new paths to alleviate suffering and improve the lives of patients.

Dr.Camel's Conclusion

This research provides hope for individuals living with Parkinson's disease, suggesting that adenosine A2A receptor antagonists could offer a new avenue for treatment. This study underscores the importance of exploring novel therapeutic targets to address complex neurological disorders.

Date :
  1. Date Completed 2011-07-14
  2. Date Revised 2023-11-05
Further Info :

Pubmed ID

18438720

DOI: Digital Object Identifier

PMC2583202

Related Literature

Article Analysis
・Side Effects of istradefylline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.