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Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients.

Author: BoloNicolas R, CohenBruce M, DanielsMelissa, HawsCharlotte, JensenJ Eric, LyooIn Kyoon, RenshawPerry F, RuscheJames R, StollAndrew L, YoonSujung J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Triacetyluridine (TAU) is a drug that is being investigated for the treatment of depression. This study found that TAU may improve symptoms of depression and improve mitochondrial function.
Paper Details　
Original Abstract of the Article :
Eleven patients with bipolar depression were given doses of up to 18 g per day of triacetyluridine (TAU) over 6 weeks to test the effect of uridine on symptoms of depression via Montgomery-Asberg Depression Rating Scale (MADRS; Asberg, Montgomery, Perris, Schalling, & Sedvall, 1978) scores and on ce...See full text at original site
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引用元：
https://doi.org/10.1037/1064-1297.16.3.199

データ提供：米国国立医学図書館（NLM）

Triacetyluridine (TAU) for Bipolar Depression: A Desert Oasis of Hope?

Bipolar depression, like a relentless desert sandstorm, can leave individuals feeling lost and depleted. Triacetyluridine (TAU), a naturally occurring compound, has shown potential as a therapeutic agent for bipolar depression. This research, like a camel caravan seeking refuge in a desert oasis, investigates the effects of TAU on depressive symptoms and brain function. The study finds that TAU may reduce depressive symptoms and improve mitochondrial function, potentially by increasing brain pH. These findings suggest that TAU could offer a novel and promising therapeutic approach for bipolar depression.

A Glimmer of Hope: TAU's Potential for Bipolar Depression

This research offers a glimmer of hope for individuals struggling with bipolar depression. The findings suggest that TAU may be a promising therapeutic agent, potentially offering a new avenue for treatment.

Navigating the Desert of Bipolar Depression: Finding New Pathways

Bipolar depression can be a challenging condition to manage. This research highlights the importance of exploring new therapeutic approaches, like TAU, to provide more effective and targeted treatments for this complex disorder.

Dr.Camel's Conclusion

This research takes us on a journey through the desert of bipolar depression, exploring the potential of TAU as a new therapeutic oasis. The findings offer a promising glimpse into a potential new treatment for this complex disorder, providing hope for those seeking relief from its debilitating effects.

Date :
  1. Date Completed 2008-11-10
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

18540779

DOI: Digital Object Identifier

10.1037/1064-1297.16.3.199

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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