Paper Details 
Original Abstract of the Article :
Pseudomonas aeruginosa is a pathogen which is known to be responsible for nosocomial infection. The appropriate use of antibiotics has become important for preventing the spread of drug-resistant P. aeruginosa. In Hara-doi Hospital, two carbapenem antibiotics, imipenem (IPM) and meropenem (MEPM), ar...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/18574658

データ提供:米国国立医学図書館(NLM)

Fighting Pseudomonas aeruginosa: The Importance of Dosage in Antibiotic Therapy

Pseudomonas aeruginosa, a common bacterium, can cause serious infections, especially in hospitalized patients. Imagine this bacterium as a pesky desert sandstorm, capable of disrupting the body's delicate equilibrium. This research explores the relationship between the dosage of the antibiotic meropenem (MEPM) and the development of MEPM-resistant Pseudomonas aeruginosa in a hospital setting.

The researchers studied the effectiveness of MEPM in treating P. aeruginosa infections in elderly patients. Their findings suggest that increasing the daily dosage of MEPM from 0.5 g to 1.0 g significantly improved the sensitivity of P. aeruginosa to MEPM. This finding highlights the importance of appropriate dosing to combat antibiotic resistance.

The Power of Dosage: A Balancing Act

This study illustrates the delicate balance between effective antibiotic treatment and the risk of developing antibiotic resistance. Choosing the right dosage is crucial for ensuring optimal treatment outcomes while minimizing the risk of resistance.

Navigating the Desert of Antibiotic Resistance

This research is a stark reminder of the escalating threat of antibiotic resistance. Finding effective ways to combat this growing problem requires ongoing research, responsible antibiotic use, and a collaborative effort to protect the efficacy of these vital medications.

Dr.Camel's Conclusion

This research is a reminder that the fight against antibiotic resistance is a constant battle. By carefully considering dosage and other factors, healthcare professionals can help minimize the development of resistance and ensure effective treatment outcomes for patients. This research is a reminder that vigilance and a commitment to responsible antibiotic use are essential for navigating the challenges of antibiotic resistance.

Date :
  1. Date Completed 2008-07-24
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18574658

DOI: Digital Object Identifier

S1341-321X(08)70767-0

Related Literature

SNS
PICO Info
in preparation
Languages

English

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