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Adverse renal and metabolic effects associated with oral sodium phosphate bowel preparation.

Author: HeherEliot C, HumphreysBenjamin D, RennkeHelmut, ThierSamuel O

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral sodium phosphate (OSP) is an effective bowel purgative used for colonoscopy preparation. However, it has been linked to electrolyte disturbances and acute kidney injury (AKI) in phosphate nephropathy, a form of nephrocalcinosis. Recent studies suggest a link between OSP and phosphate nephropathy, as well as chronic kidney disease development in elderly patients. This review summarizes current knowledge about the renal complications of OSP, its risk factors, and the pathophysiology of acute and chronic kidney damage in nephrocalcinosis.
Paper Details　
Original Abstract of the Article :
Colorectal cancer can be prevented by the removal of adenomatous polyps during screening colonoscopy, but adequate bowel preparation is required. Oral sodium phosphate (OSP), an effective bowel purgative, is available over the counter and requires a substantially lower volume than polyethylene glyco...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571150/

データ提供：米国国立医学図書館（NLM）

Sodium Phosphate: A Hidden Oasis with Potential Dangers

The field of colorectal cancer prevention, like a vast desert landscape, requires careful navigation to identify effective and safe strategies. Oral sodium phosphate (OSP) is a commonly used bowel preparation agent, offering a potentially efficient way to clear the path for colonoscopy. However, like a hidden oasis with unexpected dangers, OSP has been linked to potential renal complications. This study aims to explore the risks and implications of OSP use.

Navigating the Risks of OSP

The research, like a careful investigation into the desert's hidden dangers, reveals that OSP use is associated with a risk of electrolyte disturbances and acute kidney injury, a condition known as phosphate nephropathy. The study underscores the importance of considering individual risk factors, such as age and pre-existing kidney conditions, when deciding whether OSP is a suitable bowel preparation option.

Choosing Wisely in the Desert of Bowel Prep

This research serves as a reminder that even seemingly common procedures can have unexpected consequences, akin to navigating a desert landscape with hidden dangers. The study emphasizes the importance of informed decision-making and careful monitoring of potential risks when choosing bowel preparation methods.

Dr. Camel's Conclusion

This research, like a camel caravan venturing through a desert landscape, reveals the potential risks associated with oral sodium phosphate use. The study serves as a reminder that even seemingly safe interventions can have unintended consequences and underscores the importance of careful consideration and informed decision-making in healthcare.

Date :
  1. Date Completed 2008-11-18
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18596115

DOI: Digital Object Identifier

PMC4571150

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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