Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants.

Author: BaenzigerOskar, BauersfeldUrs, BernetVera, FreyBernhard, GantenbeinMonika Herbst, NeuhausThomas, SennhauserFelix

Paper Details 
Original Abstract of the Article :
AIM: To analyze the side effects of captopril, an angiotensin converting enzyme inhibitor (ACEI) in newborn and young infants. METHODS: Retrospective analysis of side effects in 43 patients with congenital heart disease after cardiac surgery treated with captopril for heart failure during a two-yea...See full text at original site
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引用元:
https://doi.org/10.1515/JPM.2008.064

データ提供:米国国立医学図書館(NLM)

Captopril Side Effects in Newborns and Young Infants

This research investigates the side effects of captopril, an angiotensin-converting enzyme inhibitor (ACEI), in newborns and young infants with congenital heart disease. The authors conducted a retrospective analysis of 43 patients who received captopril for heart failure following cardiac surgery. They found that side effects, including renal impairment, low blood pressure, and oxygen saturation deficits, occurred in 17 patients. These side effects were often reversible but required treatment adjustments or cessation in some cases. The authors caution that renal side effects were more common in smaller infants and recommend close monitoring of renal function, blood pressure, and oxygen saturation in infants receiving ACEI therapy.

Navigating ACEI Therapy in Infants: Balancing Benefits and Risks

This research highlights the potential side effects of captopril therapy in newborns and young infants. The authors' findings underscore the importance of careful monitoring and dose adjustments to minimize risks and optimize treatment outcomes.

Managing Congenital Heart Disease: A Collaborative Approach

Congenital heart disease can be challenging for both infants and their families. This research emphasizes the need for a collaborative approach involving healthcare professionals, parents, and caregivers to ensure the best possible care for infants with congenital heart disease.

Dr.Camel's Conclusion

This study, like a wise camel navigating the treacherous desert terrain, reminds us of the importance of careful monitoring when using ACEI therapy in infants. By understanding the potential side effects and implementing appropriate monitoring strategies, we can provide the best possible care for these vulnerable patients.

Date :
  1. Date Completed 2009-01-09
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

18605972

DOI: Digital Object Identifier

10.1515/JPM.2008.064

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SNS
PICO Info
in preparation
Languages

English

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