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Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants.
Author: BaenzigerOskar, BauersfeldUrs, BernetVera, FreyBernhard, GantenbeinMonika Herbst, NeuhausThomas, SennhauserFelix
Original Abstract of the Article :
AIM: To analyze the side effects of captopril, an angiotensin converting enzyme inhibitor (ACEI) in newborn and young infants. METHODS: Retrospective analysis of side effects in 43 patients with congenital heart disease after cardiac surgery treated with captopril for heart failure during a two-yea...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1515/JPM.2008.064
データ提供:米国国立医学図書館(NLM)
Captopril Side Effects in Newborns and Young Infants
This research investigates the side effects of captopril, an angiotensin-converting enzyme inhibitor (ACEI), in newborns and young infants with congenital heart disease. The authors conducted a retrospective analysis of 43 patients who received captopril for heart failure following cardiac surgery. They found that side effects, including renal impairment, low blood pressure, and oxygen saturation deficits, occurred in 17 patients. These side effects were often reversible but required treatment adjustments or cessation in some cases. The authors caution that renal side effects were more common in smaller infants and recommend close monitoring of renal function, blood pressure, and oxygen saturation in infants receiving ACEI therapy.
Navigating ACEI Therapy in Infants: Balancing Benefits and Risks
This research highlights the potential side effects of captopril therapy in newborns and young infants. The authors' findings underscore the importance of careful monitoring and dose adjustments to minimize risks and optimize treatment outcomes.
Managing Congenital Heart Disease: A Collaborative Approach
Congenital heart disease can be challenging for both infants and their families. This research emphasizes the need for a collaborative approach involving healthcare professionals, parents, and caregivers to ensure the best possible care for infants with congenital heart disease.
Dr.Camel's Conclusion
This study, like a wise camel navigating the treacherous desert terrain, reminds us of the importance of careful monitoring when using ACEI therapy in infants. By understanding the potential side effects and implementing appropriate monitoring strategies, we can provide the best possible care for these vulnerable patients.
Date :
- Date Completed 2009-01-09
- Date Revised 2022-04-09
Further Info :
Related Literature
English
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