Comparison of the effects of fourth-generation fluoroquinolones on corneal re-epithelialization in rabbit eyes.

Author: ChewJesse, HunterBrian, JensenMike, KleinmannGuy, MamalisNick, MeyerJay J, MoshirfarMajid, StevensScott, WernerLiliana

Paper Details 
Original Abstract of the Article :
Gatifloxacin and moxifloxacin ophthalmic solutions are frequently prescribed for antimicrobial prophylaxis following cataract and corneal refractive surgeries, although the use of topical antibiotics is likely to interfere with wound healing in the immediate postoperative period. A potential factor ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s00417-008-0893-5

データ提供:米国国立医学図書館(NLM)

The Impact of Fluoroquinolone Eye Drops on Corneal Healing

Corneal surgery is a common procedure, but the use of topical antibiotics during and after surgery can interfere with wound healing. This study compares the effects of two commonly prescribed fluoroquinolone eye drops, gatifloxacin and moxifloxacin, on corneal re-epithelialization in rabbit eyes. The study investigates the potential influence of preservation methods on wound healing, highlighting the importance of choosing appropriate medications for optimal recovery.

Gatifloxacin vs. Moxifloxacin: A Closer Look

The study found that both gatifloxacin and moxifloxacin had a negative impact on corneal re-epithelialization, with gatifloxacin, which is preserved with benzalkonium chloride, exhibiting a more pronounced effect. This suggests that the preservation method used in eye drops can influence wound healing and that unpreserved medications may be preferable in certain situations. Further research is needed to determine the optimal approach to antibiotic use during and after corneal surgery to minimize the risk of delayed healing.

Navigating the Challenges of Wound Healing

This study highlights the importance of considering the potential impact of medications on wound healing, especially in the context of surgery. Choosing the right medication, taking into account factors such as preservation methods, can be crucial for optimizing recovery and minimizing the risk of complications. Working closely with your ophthalmologist is essential to ensure that the best possible care is provided to support your healing process.

Dr. Camel's Conclusion

Imagine a camel caravan crossing a vast desert. Just as a camel's skin needs to heal from cuts and scrapes, our eyes need to heal after surgery. This study shows that some eye drops, like a harsh desert wind, can slow down the healing process. By understanding the potential impacts of different medications, we can choose the best options for our eyes, allowing them to heal effectively and ensuring a clear path through life.

Date :
  1. Date Completed 2009-01-26
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18642018

DOI: Digital Object Identifier

10.1007/s00417-008-0893-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.