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Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir.
Author: AndradeAdriana S A, BrownTodd T, CaballeroBenjamin, DobsAdrian S, FlexnerCharles W, HendrixCraig, ParsonsTeresa L, YuanChun-Su
Original Abstract of the Article :
Complementary and alternative medicine (CAM) use is prevalent among HIV-infected patients to reduce the toxicity of antiretroviral therapy. Ginseng has been used for treatment of hyperglycemia and insulin resistance, a common side effect of some HIV-1 protease inhibitors (PI). However, it is unknown...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542349/
データ提供:米国国立医学図書館(NLM)
Ginseng and Indinavir: A Potential for Interaction
This study investigates the potential interaction between American ginseng (AG) and the HIV protease inhibitor indinavir (IDV), a drug known to cause hyperglycemia and insulin resistance. The researchers examined the pharmacokinetic and metabolic effects of AG in healthy volunteers receiving IDV therapy, evaluating potential interactions between these two agents.
The findings suggest that AG may have a minor impact on the pharmacokinetics of IDV, but further research is needed to determine whether AG can effectively reverse IDV-induced insulin resistance. This exploration of potential drug interactions is like a desert traveler carefully considering the impact of a new resource on their journey, seeking a balance between benefits and risks.
Navigating the Complexities of Drug Interactions
This study highlights the importance of carefully considering potential drug interactions, especially when using complementary and alternative medicine (CAM) alongside conventional therapies. It's like a camel using its knowledge of desert plants to find safe and beneficial resources while avoiding potentially harmful ones.
A Cautionary Tale: Ginseng and Indinavir
This study underscores the importance of communicating with your healthcare provider about all medications and supplements you are taking, especially when using CAM therapies. It's like a camel using its keen senses to detect changes in the environment, adapting its behavior to ensure survival.
Dr.Camel's Conclusion
This study provides valuable insights into the potential interactions between American ginseng and indinavir. It emphasizes the need for careful monitoring and further research to fully understand the implications of using these two agents together.
Date :
- Date Completed 2008-11-24
- Date Revised 2021-10-20
Further Info :
Related Literature
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