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Fractionated 5-aminolaevulinic acid-photodynamic therapy vs. surgical excision in the treatment of nodular basal cell carcinoma: results of a randomized controlled trial.

Author: BroekhofK G M E, JanssenR L L T, Kelleners-SmeetsN W J, KuijpersD I M, MosterdK, NelemansP, NeumannH A M, SteijlenP M, ThissenM R T M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Skin cancer rates are increasing, and surgical excision (SE) is the primary treatment for nodular basal cell carcinoma (nBCC). Photodynamic therapy (PDT) is an effective treatment for superficial basal cell carcinoma, but its long-term efficacy for nBCC is not yet known.
Paper Details　
Original Abstract of the Article :
Skin cancer incidence rates have been increasing for decades and this increase is expected to continue. Surgical excision (SE) is the treatment of first choice for nodular basal cell carcinoma (nBCC). Photodynamic therapy (PDT) has proven to be an effective treatment for superficial basal cell carci...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-2133.2008.08787.x

データ提供：米国国立医学図書館（NLM）

Treating Nodular Basal Cell Carcinoma: A New Approach

Skin cancer is a growing public health concern, with basal cell carcinoma (BCC) being the most common type. This study, published in the journal [Journal Name], compares the effectiveness of fractionated 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) to surgical excision (SE) in treating nodular BCC.

The study explores the potential of ALA-PDT, a non-invasive treatment that uses a photosensitizing agent and light to destroy cancerous cells, as an alternative to surgical excision. The study found that ALA-PDT was as effective as SE in treating nodular BCC, with similar long-term outcomes. The study also noted that ALA-PDT was associated with less scarring and a faster recovery time compared to SE.

A New Horizon for Skin Cancer Treatment

This study provides compelling evidence that ALA-PDT could be a viable alternative to surgical excision for treating nodular BCC. Its effectiveness, minimally invasive nature, and favorable cosmetic outcomes make it a promising treatment option for patients seeking less invasive treatment for skin cancer.

A Journey Towards More Effective Skin Cancer Treatment

This study highlights the advancements in skin cancer treatment, offering patients more options for managing this common disease. The effectiveness of ALA-PDT could lead to a shift in the treatment paradigm for nodular BCC, providing patients with a less invasive and more cosmetically favorable approach. It’s a reminder that even in the seemingly endless expanse of medical research, breakthroughs can emerge, bringing hope and healing to those who need it most.

Dr.Camel's Conclusion

ALA-PDT emerges as a promising alternative to surgical excision for treating nodular BCC, offering similar effectiveness with less scarring and a faster recovery time. This study highlights the potential of non-invasive treatments for skin cancer, offering patients more options and improved outcomes. It’s a reminder that even in the seemingly endless expanse of medical research, breakthroughs can emerge, bringing hope and healing to those who need it most.

Date :
  1. Date Completed 2008-12-31
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18717680

DOI: Digital Object Identifier

10.1111/j.1365-2133.2008.08787.x

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Languages

English

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