Paper Details
- Home
- Paper Details
Antipsychotics possessing antidepressive efficacy increase Golf protein in rat striatum.
Author: EndoShiro, HamamuraTakashi, IshiharaTakeshi, KurodaShigetoshi, MiyataShinji, TaokaHideki, TomaKishio
Original Abstract of the Article :
Recently, second-generation antipsychotics (SGAs) have been widely used in the treatment of mood disorders. However, the mechanisms of the antidepressant effect of SGAs remain unclear. We proposed that Golf protein, a stimulant alpha-subunit of G protein coupled with the dopamine D1 receptor, might ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00213-008-1264-y
データ提供:米国国立医学図書館(NLM)
Exploring the Antidepressant Effects of Antipsychotics
This research explores the intriguing world of antipsychotics, which are commonly used to treat mental health conditions like schizophrenia. It's like delving into the mysterious depths of a desert oasis – we know they're there, but how they work is still being uncovered. This study focuses on a specific protein called Golf, which plays a role in how the brain processes dopamine, a neurotransmitter linked to mood.
Antipsychotics and the Golf Protein
The study found that certain antipsychotics, particularly those used for mood disorders, can increase the levels of Golf protein in the brain. This is like finding a hidden spring of water in the desert – it could be a key to understanding how these drugs work. The researchers believe that Golf protein may be involved in the antidepressant effects of these antipsychotics.
The Mystery Continues
This study is just one step in understanding the complex mechanisms of antipsychotics. It's like discovering a new path in the desert – it opens up possibilities for further research. We still need to learn more about how Golf protein works and how it interacts with antipsychotics to unlock their full potential in treating mood disorders.
Dr. Camel's Conclusion
This research brings us closer to understanding the intricate interplay between the brain, mood, and antipsychotics. It's a journey of discovery, much like traversing a vast desert, with many mysteries yet to be revealed. By unraveling these mysteries, we can pave the way for more effective treatment of mental health conditions.
Date :
- Date Completed 2009-03-24
- Date Revised 2021-10-20
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.