A new scalp formulation of calcipotriol plus betamethasone dipropionate compared with each of its active ingredients in the same vehicle for the treatment of scalp psoriasis: a randomized, double-blind, controlled trial.

Author: AnsteyA, BarnesL, BolducC, HoffmannV, ReichK, SaariS, SegaertS, VaillantL, van de KerkhofP C M

Paper Details 
Original Abstract of the Article :
BACKGROUND: There is a need for new treatments for scalp psoriasis, as many topical treatments are cosmetically unacceptable and difficult to apply, resulting in poor compliance. OBJECTIVES: To compare the efficacy and safety of a new, once-daily, two-compound scalp formulation (Xamiol; LEO Pharma ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2133.2008.08927.x

データ提供:米国国立医学図書館(NLM)

Scalp Psoriasis Treatment: A New Formulation Offers Hope

Scalp psoriasis, a common skin condition, can be challenging to treat effectively due to the difficulty of applying topical treatments and their potential cosmetic drawbacks. This research introduces a new scalp formulation, Xamiol, containing a combination of calcipotriol and betamethasone dipropionate. The study aimed to compare the efficacy and safety of this combined formulation with its individual components in treating scalp psoriasis. The researchers conducted a double-blind, randomized, controlled trial involving adult patients with scalp psoriasis. The study found that the combined formulation was significantly more effective in achieving clear or almost clear scalps compared to either of its individual components. This finding is particularly encouraging for patients seeking a more effective and well-tolerated treatment option for scalp psoriasis.

A Two-Compound Solution: Superior Efficacy and Safety

The study revealed a statistically significant difference in the proportion of patients achieving clear or almost clear scalps with the combined formulation compared to the single-compound treatments. This suggests that the combination of calcipotriol and betamethasone dipropionate offers a synergistic effect, leading to greater therapeutic efficacy. Additionally, the combined formulation was associated with a lower incidence of adverse events, further supporting its safety and tolerability. These findings suggest that the combined formulation offers a promising new therapeutic option for scalp psoriasis.

A More Comfortable Journey for Scalp Psoriasis Patients

The study highlights the potential of Xamiol to provide a more effective and comfortable treatment experience for scalp psoriasis patients. The combination of calcipotriol and betamethasone dipropionate appears to offer a superior therapeutic profile, resulting in improved efficacy and reduced side effects. This discovery could lead to improved treatment outcomes and enhanced quality of life for individuals struggling with scalp psoriasis.

Dr.Camel's Conclusion

Just as a camel's hump provides a reservoir of energy for its journey across the desert, this new scalp formulation offers a potent and well-tolerated solution for the challenging journey of managing scalp psoriasis. The study's findings provide hope for a more effective and comfortable treatment experience for patients with this common skin condition.

Date :
  1. Date Completed 2009-02-17
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

19067709

DOI: Digital Object Identifier

10.1111/j.1365-2133.2008.08927.x

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PICO Info
in preparation
Languages

English

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