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Lubiprostone for chronic idiopathic constipation and irritable bowel syndrome with constipation.
Author: CheyWilliam D, SaadRichard
Original Abstract of the Article :
Lubiprostone, a locally acting highly selective type-2 chloride channel activator, has been US FDA approved since January 2006 for the treatment of adults with chronic idiopathic constipation and FDA approved since April 2008 for the treatment of woman aged 18 years or older suffering from irritable...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1586/17474124.2.4.497
データ提供:米国国立医学図書館(NLM)
Lubiprostone: A Novel Treatment for Constipation
This study explores the efficacy of [lubiprostone], a locally acting highly selective type-2 chloride channel activator, in treating [chronic idiopathic constipation] and [irritable bowel syndrome (IBS) with constipation]. The study highlights the mechanism of action of lubiprostone, which promotes fluid secretion in the intestines, leading to increased stool liquidity and accelerated bowel transit. Clinical trials have demonstrated the effectiveness of lubiprostone in both short- and long-term treatments, showing significant improvement in bowel movements, stool consistency, and overall quality of life.
Lubiprostone: A Promising Treatment for Constipation
Lubiprostone has emerged as a promising treatment option for chronic idiopathic constipation and irritable bowel syndrome (IBS) with constipation. The study highlights its effectiveness in increasing spontaneous bowel movements, improving stool consistency, and reducing constipation severity. Furthermore, the study emphasizes the lack of evidence for rebound constipation or IBS symptoms following the cessation of lubiprostone therapy.
Lubiprostone: A Potential Solution for Digestive Discomfort
This study offers hope for individuals suffering from constipation and IBS with constipation. Lubiprostone's ability to promote fluid secretion and accelerate bowel transit provides a potential solution for digestive discomfort. The study underscores the importance of consulting a healthcare professional to determine the best treatment option for individual needs.
Dr.Camel's Conclusion
Think of lubiprostone as a gentle desert wind that helps to loosen the sand, making it easier for a camel to move along a difficult path. In the same way, lubiprostone works to ease the movement of waste through the digestive system, providing relief from the discomfort of constipation and IBS. This research sheds light on the potential of targeted therapies for digestive disorders, paving the way for a smoother journey through the desert of digestive health.
Date :
- Date Completed 2009-03-06
- Date Revised 2015-11-19
Further Info :
Related Literature
English
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