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[Evaluation of the adverse effects of nevirapine in HIV-infected pregnant women in a South Brazilian University Hospital].
Author: AstoriAdriane de Assis Fischer de, FernandesRachelle de Brito, GomesSuria El-Kouba, KondoWilliam, SasakiMaria das Graças, SbalqueiroRenato Luiz
Original Abstract of the Article :
PURPOSE: The aim of this article is to evaluate the use of nevirapine HIV-infected pregnant women in our service. METHODS: a retrospective study was performed between January 2003 and December 2006 analysing all women prescribed nevirapine in pregnancy. Exclusion criteria included: (1) women who st...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1590/s0100-72032008000100004
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of HIV Treatment: Evaluating the Safety of Nevirapine
The desert of HIV research continues to be a challenging landscape, with ongoing efforts to develop safe and effective treatment strategies. This research evaluates the use of nevirapine, a non-nucleoside reverse transcriptase inhibitor, in HIV-infected pregnant women. The authors conducted a retrospective study, analyzing the incidence of adverse hepatic and/or cutaneous effects associated with nevirapine use during pregnancy.
A Journey Through the Desert of Adverse Effects: Exploring Nevirapine's Impact
The study reveals that nevirapine use in pregnant women is associated with a high incidence of adverse events, primarily cutaneous reactions. The authors found no correlation between high CD4 counts and adverse events, suggesting that the risk of nevirapine-related toxicity may be independent of immune status. These findings highlight the importance of careful monitoring and management of potential adverse effects during nevirapine treatment.
The Desert of HIV Treatment: Finding Safe and Effective Strategies
This research underscores the importance of balancing the potential benefits of nevirapine with the risk of adverse effects. The authors highlight the need for ongoing research to develop safer and more effective antiretroviral therapies, particularly for pregnant women. The study emphasizes the importance of individualized treatment plans that consider patient-specific factors, including CD4 count and potential drug interactions.
Dr. Camel's Conclusion
This study provides valuable insights into the potential risks and benefits of nevirapine treatment in pregnant women with HIV. The findings underscore the importance of careful monitoring for adverse effects and the ongoing need for research to develop safer and more effective antiretroviral therapies.
Date :
- Date Completed 2009-07-15
- Date Revised 2019-11-11
Further Info :
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