Effects of mesalamine (5-aminosalicylic acid) on bacterial gene expression.

Author: GriffithsTanya A, KaufmanJaime, NessSusan, RiouxKevin P, SuretteMichael G

Paper Details 
Original Abstract of the Article :
5-Aminosalicylic acid (5-ASA) is a well-established treatment for inflammatory bowel disease (IBD) and may reduce the risk of colon cancer in patients with chronic colitis, but the mechanisms underlying these effects have not been fully elucidated. Although 5-ASA delivery is targeted to the distal g...See full text at original site
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引用元:
https://doi.org/10.1002/ibd.20876

データ提供:米国国立医学図書館(NLM)

Mesalamine and Bacterial Gene Expression: A Deeper Look into IBD

Inflammatory bowel disease (IBD) is a complex and chronic condition that affects the digestive tract. It's like a camel struggling to find nourishing vegetation in a desert ravaged by drought.

This study examines the impact of mesalamine (5-aminosalicylic acid) on bacterial gene expression in the gut. Researchers aimed to understand the [main objective] of this drug on the gut microbiome, particularly its potential to influence the bacteria that contribute to IBD.

The study suggests that mesalamine can influence bacterial gene expression in the gut, potentially contributing to its therapeutic effects in IBD. The key findings include [key findings], highlighting the importance of considering the gut microbiome in IBD management.

Navigating the Desert of IBD

This study sheds light on the complex interplay between the gut microbiome and IBD. It's like understanding the different types of vegetation in a desert and how they can either contribute to or hinder a camel's survival.

Finding Balance in the Desert of IBD

This research reminds us that the gut microbiome plays a crucial role in overall health, particularly in conditions like IBD. By understanding the impact of drugs like mesalamine on the gut microbiome, we can develop more targeted and personalized treatment strategies.

Dr. Camel's Conclusion

This study emphasizes the importance of considering the gut microbiome in the management of IBD. It's like recognizing that the desert ecosystem is a complex interplay of various elements, requiring a holistic approach for optimal health.

Date :
  1. Date Completed 2009-09-01
  2. Date Revised 2018-09-13
Further Info :

Pubmed ID

19202572

DOI: Digital Object Identifier

10.1002/ibd.20876

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Languages

English

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