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Alpha-methyldopa hepatotoxicity in pregnancy.

Author: AliTauseef, LeVu, RizviSyed, SrinivasanNandakumar

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A 33-year-old pregnant woman was diagnosed with methyldopa-induced hepatitis. She presented with jaundice and changed urine color. Liver function tests revealed elevated transaminases, and she was treated with prednisone. Two weeks later, liver enzyme levels returned to normal.
Paper Details　
Original Abstract of the Article :
A 12-week pregnant, 33-year-old African American female, presented with jaundice and change in urine colour. Liver function tests revealed raised transamines and normal alkaline phosphatase. She was started on methyldopa 6 weeks prior to presentation. After initial negative investigations including ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/19208320

データ提供：米国国立医学図書館（NLM）

Alpha-Methyldopa and Pregnancy: A Case of Hepatotoxicity

The field of obstetrics and gynecology addresses the complex interplay between medications and pregnancy. This case report presents a pregnant patient who developed jaundice and changes in urine color after starting methyldopa, an antihypertensive medication. The patient's liver function tests revealed elevated transaminases, a sign of liver damage. The case highlights the potential for methyldopa to induce hepatotoxicity, a rare but serious side effect during pregnancy.

Methyldopa and Hepatotoxicity in Pregnancy

This case demonstrates the potential risk of methyldopa-induced hepatotoxicity during pregnancy. While rare, this adverse effect can be serious and requires prompt recognition and management. The case emphasizes the importance of closely monitoring pregnant patients on methyldopa for any signs of liver dysfunction and ensuring appropriate medical intervention when necessary.

Medication Safety During Pregnancy

Medication use during pregnancy requires careful consideration. Consulting a healthcare professional to discuss potential risks and benefits of any medication is crucial. Understanding the potential side effects and monitoring for any changes in health status are essential for ensuring the well-being of both mother and fetus.

Dr.Camel's Conclusion

Pregnancy is a delicate journey, much like navigating a vast desert with its shifting sands. Understanding the potential risks and benefits of medications is crucial for ensuring a safe and healthy journey for both mother and child.

Date :
  1. Date Completed 2009-05-14
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

19208320

DOI: Digital Object Identifier

02.2009/JCPSP.125126

Related Literature

Article Analysis
・Side Effects of methyldopa
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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