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Short- and long-term effects of silodosin, a selective alpha 1A-adrenoceptor antagonist, on ejaculatory function in rats.

Author: FukagawaAtsushi, ImanishiAya, LatifpourJamshid, YamamotoYasuhiro, YonoMakoto, YoshidaMasaki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Silodosin is a medication used to treat enlarged prostate. This study examined the effects of silodosin on the ability of rats to ejaculate. Silodosin was found to have both short- and long-term effects on ejaculation and on the receptors in the prostate.
Paper Details　
Original Abstract of the Article :
To investigate the short- and long-term effects of silodosin, a selective alpha(1A)-adrenoceptor antagonist, on spontaneous seminal emission by isolated rats and on the properties of alpha(1)-adrenoceptor subtypes in the rat seminal vesicle, as silodosin produces a relatively high incidence rate of ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1464-410X.2009.08364.x

データ提供：米国国立医学図書館（NLM）

Exploring the Effects of Silodosin on Ejaculatory Function in Rats

This research delves into the intricate world of male reproductive health. It focuses on the impact of silodosin, a medication used to treat an enlarged prostate, on ejaculatory function. Researchers used rats to study the short-term and long-term effects of silodosin, a selective alpha 1A-adrenoceptor antagonist, on seminal emission. This research is important because it sheds light on potential side effects of commonly prescribed medications, particularly those affecting sexual health.

Silodosin's Effects on Ejaculatory Function

The study found that silodosin can significantly impact ejaculatory function in rats. It demonstrated both short-term and long-term effects on spontaneous seminal emission. This is a crucial finding because it suggests that silodosin may cause similar side effects in humans, potentially leading to issues related to fertility and sexual satisfaction.

Navigating Medication Side Effects

This research highlights the importance of open communication between patients and healthcare providers about potential medication side effects, especially those related to sexual health. It emphasizes the need for careful consideration of the potential risks and benefits of any medication, particularly for those who may be concerned about sexual function.

Dr. Camel's Conclusion

This study provides valuable insights into the effects of a widely used medication on reproductive health. It serves as a reminder to carefully consider the potential side effects of medications, especially those that can impact sensitive areas like sexual function. This research is an important step toward developing more effective and safer treatment options for men with an enlarged prostate.

Date :
  1. Date Completed 2009-07-10
  2. Date Revised 2013-05-22
Further Info :

Pubmed ID

19220259

DOI: Digital Object Identifier

10.1111/j.1464-410X.2009.08364.x

Related Literature

Article Analysis
・Effects of silodosin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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