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[An effect of perindopril on the level of tumor necrosis factor-alpha and matrix metalloproteinase-9 in peripheral blood in the acute period of atherothrombotic ischemic stroke and myocardial infarction].
Author: EreminI I, KonstantinovaE V, ShostakN A, ShurdumovaM Kh, SkvortsovaV I
Original Abstract of the Article :
Twenty-nine patients with acute atherothrombotic ischemic stroke and 36 patients with acute Q-wave myocardial infarction have been studied. Each group has been stratified into 2 subgroups: patients of subgroups A received an ACE inhibitor perindopril in the complex therapy from the 1st day of diseas...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/19425365
データ提供:米国国立医学図書館(NLM)
Perindopril: A Potential Oasis in the Desert of Stroke and Heart Attack
Dr. Camel here, delving into the complexities of cardiovascular disease, a condition that can be as unpredictable as a desert sandstorm. This study examines the effects of perindopril, an ACE inhibitor, on patients who have experienced either an ischemic stroke or a myocardial infarction (heart attack). The researchers looked at the levels of tumor necrosis factor-alpha (TNF-α) and matrix metalloproteinase-9 (MMP-9), both of which play important roles in inflammation and tissue damage after these events.
Perindopril's Protective Effects
The study found that perindopril did not cause any significant side effects and may even reduce the activity of MMP-9, potentially contributing to a protective effect. This suggests that perindopril could be a valuable tool for managing these conditions.
Navigating the Desert of Cardiovascular Disease
This research highlights the importance of managing cardiovascular disease with appropriate medications and therapies. It underscores the need for careful monitoring of patients after stroke or heart attack to ensure they receive the best possible care.
Dr.Camel's Conclusion
This study provides valuable insights into the potential benefits of perindopril in managing ischemic stroke and myocardial infarction. It suggests that this medication could offer a protective effect by reducing inflammation and tissue damage. This research underscores the importance of finding new and effective treatments for cardiovascular disease, a condition that affects millions worldwide.
Date :
- Date Completed 2009-06-09
- Date Revised 2016-10-18
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