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Interferon therapy during the plateau phase of multiple myeloma: an update of a Swedish multicenter study.

Author: WestinJ

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A study of 308 patients with multiple myeloma randomized 120 patients in a plateau phase to receive either no further treatment or continuous interferon-alfa-2b therapy. Interferon therapy significantly prolonged the plateau phase compared to no therapy, with a median plateau duration of 59 weeks versus 26 weeks. Early data suggest a lower mortality rate for patients receiving interferon.
Paper Details　
Original Abstract of the Article :
Over the course of a 2-year period (September 1987 to September 1989) a total of 432 patients with multiple myeloma were registered in a study comprising 39 Swedish and one Italian clinics. Six of these were university hospitals, the others were county (community) hospitals. A total of 308 patients ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1948128

データ提供：米国国立医学図書館（NLM）

Interferon Therapy for Multiple Myeloma: Exploring New Avenues for Treatment

The desert of cancer research is vast and complex, with multiple myeloma being a particularly difficult foe. This research investigates the potential benefits of interferon therapy for patients with multiple myeloma who have reached a plateau phase in their disease. The researchers, like skilled desert guides, compared the outcomes of patients receiving interferon treatment to those receiving no further therapy, seeking to determine the impact of this treatment on disease progression and survival.

A New Oasis in Multiple Myeloma Treatment: Evaluating the Effectiveness of Interferon Therapy

The study, like a well-marked trail through the desert, revealed that interferon therapy significantly prolonged the duration of the plateau phase in patients with multiple myeloma. The findings suggest that interferon could be a valuable tool for managing the disease and improving patient outcomes. This discovery is like finding a hidden oasis in the desert, offering hope for patients with this challenging condition.

Navigating the Desert of Cancer Treatment: Seeking Effective and Personalized Therapies

This research underscores the importance of exploring personalized treatment strategies for cancer patients. The findings suggest that interferon therapy could be a beneficial option for patients with multiple myeloma who have reached a plateau phase. It highlights the importance of carefully considering individual patient needs and disease characteristics when selecting the most appropriate treatment approach.

Dr.Camel's Conclusion

This study provides valuable insights into the management of multiple myeloma. Interferon therapy, with its ability to prolong the plateau phase, could be a key player in improving patient outcomes. As we continue to explore the desert of cancer research, we must strive to develop targeted and personalized therapies that address the specific needs of each patient.

Date :
  1. Date Completed 1991-12-10
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

1948128

DOI: Digital Object Identifier

0093-7754(91)90040-T

Related Literature

Article Analysis
・Effective treatment of multiple myeloma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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