Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatment.

Author: , DanknerWayne M, FentonTerence, GonaPhilimon, HuangSharon, NachmanSharon, Patterson-BartlettJulie, ReadJennifer S, WeinbergAdriana

Paper Details 
Original Abstract of the Article :
BACKGROUND: HIV-infected individuals mount poor antibody responses to vaccines. We sought to identify the immunologic and virologic factors associated with a robust response to hepatitis A virus (HAV) vaccine in children on highly active antiretroviral treatment. METHODS: One hundred fifty-two pedi...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19617848

データ提供:米国国立医学図書館(NLM)

Hepatitis A Vaccine in HIV-Infected Children: A Journey Through the Desert of Immunodeficiency

HIV infection weakens the immune system, making individuals more susceptible to infections. This study examines the antibody responses to hepatitis A virus (HAV) vaccine in HIV-infected children on highly active antiretroviral treatment (HAART). The research investigates the virologic and immunologic factors associated with a robust antibody response to the HAV vaccine.

Building Immunity in the Desert: The Challenge of Vaccination in HIV-Infected Children

The study reveals that a robust antibody response to the HAV vaccine is associated with controlled viral replication, preserved or reconstituted CD19+ and CD4+ cell numbers and function. This research suggests that HAART plays a crucial role in improving vaccine efficacy in HIV-infected children. However, the study also highlights the need for further investigation into the mechanisms underlying the immune response to vaccines in this population.

A Oasis of Hope in the Desert of HIV: Vaccinating for a Healthier Future

This research offers a glimmer of hope for HIV-infected children, demonstrating the potential for effective vaccination with HAART. It underscores the importance of continued research to optimize vaccine strategies and ensure a healthier future for individuals living with HIV.

Dr.Camel's Conclusion

This research, like a flickering candle in the desert of HIV, sheds light on the challenges and possibilities of vaccination in this vulnerable population. It inspires us to continue seeking innovative solutions to improve the health and well-being of individuals living with HIV.

Date :
  1. Date Completed 2009-09-24
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19617848

DOI: Digital Object Identifier

NIHMS176072

Related Literature

SNS
PICO Info
in preparation
Languages

English

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