Effects of bisacodyl on ascending colon emptying and overall colonic transit in healthy volunteers.

Author: BurtonD D, CamilleriM, CremoniniF, ManabeN, SandbornW J

Paper Details 
Original Abstract of the Article :
BACKGROUND: The mechanism of action of bisacodyl in the unprepared human colon remains unclear. AIM: To evaluate the effect of oral bisacodyl on the overall and regional colonic transit in humans. METHODS: In a double-blind, randomized, placebo-controlled study of 25 healthy participants, effects ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19678812

データ提供:米国国立医学図書館(NLM)

Bisacodyl: A Deeper Dive into its Mechanism of Action

The quest for a better understanding of how medications work is an endless journey. This study focuses on bisacodyl, a common laxative, and investigates its effects on colonic transit in healthy volunteers. It's like peering into the complex machinery of the digestive system, seeking to decipher the mechanisms of action of this familiar drug.

Bisacodyl Specifically Targets the Ascending Colon

The study revealed that bisacodyl significantly accelerates emptying in the ascending colon, the first part of the large intestine. It's like uncovering a specific target within the vast desert of the digestive system, where bisacodyl exerts its primary action. This finding sheds light on the specific mechanism by which bisacodyl alleviates constipation.

Understanding Bisacodyl's Role in Constipation Relief

This research provides valuable insights into the mechanism of action of bisacodyl, a widely used laxative. It's like finding a hidden path through the desert of constipation, offering a better understanding of how this medication works. These findings contribute to a deeper understanding of how bisacodyl works, paving the way for more targeted and effective treatment approaches for constipation.

Dr. Camel's Conclusion

This study reveals the intricate workings of bisacodyl within the digestive system. It's like uncovering a hidden spring within the desert of bowel movements. By focusing its action on the ascending colon, bisacodyl effectively promotes regular bowel function, providing relief from constipation. It's a testament to the ongoing quest for understanding the complexities of our bodies and finding solutions to common ailments.

Date :
  1. Date Completed 2010-02-26
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19678812

DOI: Digital Object Identifier

NIHMS141734

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Languages

English

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