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[Therapy study of chronic polyarthritis with sulfasalazine with special emphasis on the profile of side effects].

Author: LonauerG

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
English AbstractA summary of a research paper/publication written in English for a wider audience.

Overview

Sulfasalazine was effective in treating rheumatoid arthritis in 58.7% of patients, but side effects occurred in 40.5% of patients, mostly within the first four months of treatment.
Paper Details　
Original Abstract of the Article :
138 patients, suffering from rheumatoid arthritis, were treated with sulfasalazine for up to 43 months. In 58.7% of the patients a good or moderate effect was ascertained. Side-effects occurred in 40.5% of the treated patients, mostly in the first 4 months after starting treatment, but some of the m...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1970208

データ提供：米国国立医学図書館（NLM）

Sulfasalazine for Chronic Polyarthritis: A Comprehensive Look

Chronic polyarthritis, a condition characterized by persistent joint inflammation, is a formidable foe. This study investigated the effectiveness and safety of sulfasalazine, a medication commonly used to treat inflammatory bowel disease, in treating rheumatoid arthritis, a type of chronic polyarthritis. The study aimed to assess the drug's efficacy and profile potential side effects, providing insights into its therapeutic potential.

Sulfasalazine: A Promising but Complex Treatment

The study found that sulfasalazine demonstrated a moderate to good effect in nearly 60% of patients with rheumatoid arthritis. However, it also highlighted the importance of closely monitoring patients for side effects. While most side effects occurred early in treatment, some serious adverse reactions emerged later. The study emphasizes the need for regular laboratory tests to ensure patient safety and monitor for potential drug-related complications.

Managing Side Effects: A Collaborative Approach

The study underscores the need for a cautious approach to using sulfasalazine for rheumatoid arthritis. Close monitoring of laboratory parameters, such as liver enzymes, kidney function, and blood cell counts, is crucial. Patients should be aware of potential side effects and work closely with their healthcare provider to manage any complications.

Dr.Camel's Conclusion

The study offers a comprehensive view of sulfasalazine's potential benefits and risks in the treatment of rheumatoid arthritis. While the drug demonstrates promise, it requires careful monitoring and personalized management to ensure optimal outcomes and mitigate potential side effects. Just as a desert traveler needs to be vigilant about hydration and prepare for unexpected challenges, individuals taking sulfasalazine should be aware of the potential risks and work closely with their healthcare provider to navigate their treatment journey.

Date :
  1. Date Completed 1990-05-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1970208

DOI: Digital Object Identifier

1970208

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Article Analysis
・Side Effects of sulfasalazine
SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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