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Folate-mediated solid-liquid lipid nanoparticles for paclitaxel-coated poly(ethylene glycol).
Author: TangCui, WuLifang, YinChunhua
Original Abstract of the Article :
BACKGROUND: As a promising anticancer drug, severe side-effects of current clinical formulations for paclitaxel have restricted its use, developing a better technical-economical formulation for paclitaxel delivery is needed. METHOD: In this study, the compound of folate-poly(ethylene glycol) (PEG)-...See full text at original site
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引用元:
https://doi.org/10.3109/03639040903244472
データ提供:米国国立医学図書館(NLM)
A New Way to Deliver Paclitaxel: Folate-Mediated Solid-Liquid Lipid Nanoparticles
In the vast desert of cancer treatment, researchers are constantly searching for new oases of hope. This study explores the potential of [folate-mediated solid-liquid lipid nanoparticles (SLLN)] as a novel delivery system for the cancer drug [paclitaxel]. The researchers designed these nanoparticles to target cancer cells specifically, potentially reducing the side effects associated with traditional paclitaxel formulations. Their results indicate that [paclitaxel-loaded SLLN exhibited a longer and sustained in vitro releasing property], and in animal studies, [the S180 tumor-bearing mice treated with paclitaxel-loaded SLLN exhibited higher tumor inhibition rate] compared to traditional paclitaxel injections. This promising finding suggests that folate-mediated SLLN could be a valuable new weapon in the fight against cancer.
Folate-Mediated SLLN: A Targeted Approach to Cancer Treatment
This study proposes a unique approach to delivering paclitaxel, potentially improving its effectiveness and reducing side effects. The use of folate to target cancer cells could be a game-changer in cancer treatment, offering a more precise and potent attack on tumors. This could lead to improved treatment outcomes and a better quality of life for patients battling cancer.
Navigating the Desert of Cancer Treatment: Hope on the Horizon
This study underscores the importance of continued research and development in the fight against cancer. The development of new delivery systems like folate-mediated SLLN offers a glimmer of hope in the desert of cancer treatment. It's a testament to the ingenuity and dedication of researchers who are constantly striving for new ways to improve patient outcomes and make the journey through cancer treatment a little less challenging.
Dr. Camel's Conclusion
This research explores the potential of a novel drug delivery system, folate-mediated SLLN, for paclitaxel. This approach could provide a targeted and effective way to deliver this vital drug, potentially leading to improved treatment outcomes and a better quality of life for cancer patients. The desert of cancer treatment is vast and challenging, but research like this provides a beacon of hope, guiding us towards a future where we can conquer this formidable foe.
Date :
- Date Completed 2010-10-12
- Date Revised 2018-12-01
Further Info :
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