Dosimetry of 90Y-ibritumomab tiuxetan as consolidation of first remission in advanced-stage follicular lymphoma: results from the international phase 3 first-line indolent trial.

Author: AntonescuCristian, DelaloyeAngelika Bischof, HagenbeekAnton, KuhlmannJens, LoutonThomas

Paper Details 
Original Abstract of the Article :
UNLABELLED: The objective of this analysis was to assess the radiation exposure associated with (90)Y-ibritumomab tiuxetan when used as consolidation therapy in adults with low or minimal tumor burden after first-line therapy of advanced follicular lymphoma (FL). METHODS: The patients who were enro...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.2967/jnumed.109.067587

データ提供:米国国立医学図書館(NLM)

Targeted Radiation Therapy: A Precise Approach to Follicular Lymphoma

Follicular lymphoma is a type of non-Hodgkin lymphoma that can be challenging to treat. This study explores the use of (90)Y-ibritumomab tiuxetan, a targeted radioimmunotherapy, as consolidation therapy for patients with advanced follicular lymphoma. The authors investigated the radiation exposure associated with this treatment and its correlation with clinical outcomes.

A Precision Strike: Dosimetry and Clinical Outcomes in Follicular Lymphoma

The study found that (90)Y-ibritumomab tiuxetan, when used as consolidation therapy, delivered significant radiation doses to the bone marrow and whole body. Interestingly, progression-free survival was positively correlated with both whole-body and bone marrow radiation doses. This suggests that targeted radiation therapy may be an effective strategy for improving long-term outcomes in patients with follicular lymphoma.

A New Frontier in Cancer Treatment: Targeted Radioimmunotherapy

This research highlights the potential of targeted radioimmunotherapy as a promising approach for treating certain types of cancer. The study's findings encourage further exploration of this treatment modality, particularly in the context of follicular lymphoma and other cancers where precision targeting may offer significant benefits.

Dr.Camel's Conclusion

This research demonstrates the power of precision in the desert of cancer treatment. Targeted radioimmunotherapy, like (90)Y-ibritumomab tiuxetan, offers a new frontier for tackling this complex disease. It's a reminder that by focusing our efforts with precision, we can achieve remarkable results in the battle against cancer.

Date :
  1. Date Completed 2009-12-03
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

19837764

DOI: Digital Object Identifier

10.2967/jnumed.109.067587

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.