Effects of garcinol and guttiferone K isolated from Garcinia cambogia on oxidative/nitrative modifications in blood platelets and plasma.

Author: KolodziejczykJoanna, MasulloMilena, OlasBeata, PiacenteSonia, WachowiczBarbara

Paper Details 
Original Abstract of the Article :
The effects of garcinol and guttiferone K, two polyisoprenylated benzophenones occurring a food plant called Garcinia cambogia, on oxidative/nitrative protein damage (determined by parameters such as levels of protein carbonyl groups and nitrotyrosine residues) in human blood platelets and plasma af...See full text at original site
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引用元:
https://doi.org/10.3109/09537100903165182

データ提供:米国国立医学図書館(NLM)

Exploring the Antioxidant Potential of Garcinol and Guttiferone K in Blood Platelets

Oxidative stress, a major contributor to various health issues, involves an imbalance between free radical production and antioxidant defenses. This study investigates the antioxidant effects of garcinol and guttiferone K, compounds found in the Garcinia cambogia fruit, on oxidative damage in human blood platelets and plasma. The researchers conducted in vitro experiments to evaluate the ability of these compounds to protect against oxidative damage induced by peroxynitrite, a potent oxidant.

Garcinol and Guttiferone K Show Protective Effects Against Oxidative Stress

The study revealed that both garcinol and guttiferone K significantly reduced protein carbonyl formation and lipid peroxidation in blood platelets and plasma exposed to peroxynitrite. This suggests that these compounds may have potential antioxidant properties, potentially contributing to the prevention of diseases related to oxidative stress.

Antioxidant Power From Nature's Bounty

This research exemplifies the untapped potential of natural compounds like garcinol and guttiferone K, highlighting their potential to combat oxidative stress. It reminds us that a vast desert of natural remedies awaits exploration, offering promising solutions to various health challenges.

Dr. Camel's Conclusion

This study provides a fascinating glimpse into the potential of natural compounds as antioxidants. Garcinol and guttiferone K emerge as promising candidates for further investigation, offering a path towards the development of novel antioxidant-based therapies.

Date :
  1. Date Completed 2010-02-18
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

19852687

DOI: Digital Object Identifier

10.3109/09537100903165182

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SNS
PICO Info
in preparation
Languages

English

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