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Effects of garcinol and guttiferone K isolated from Garcinia cambogia on oxidative/nitrative modifications in blood platelets and plasma.
Author: KolodziejczykJoanna, MasulloMilena, OlasBeata, PiacenteSonia, WachowiczBarbara
Original Abstract of the Article :
The effects of garcinol and guttiferone K, two polyisoprenylated benzophenones occurring a food plant called Garcinia cambogia, on oxidative/nitrative protein damage (determined by parameters such as levels of protein carbonyl groups and nitrotyrosine residues) in human blood platelets and plasma af...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3109/09537100903165182
データ提供:米国国立医学図書館(NLM)
Exploring the Antioxidant Potential of Garcinol and Guttiferone K in Blood Platelets
Oxidative stress, a major contributor to various health issues, involves an imbalance between free radical production and antioxidant defenses. This study investigates the antioxidant effects of garcinol and guttiferone K, compounds found in the Garcinia cambogia fruit, on oxidative damage in human blood platelets and plasma. The researchers conducted in vitro experiments to evaluate the ability of these compounds to protect against oxidative damage induced by peroxynitrite, a potent oxidant.
Garcinol and Guttiferone K Show Protective Effects Against Oxidative Stress
The study revealed that both garcinol and guttiferone K significantly reduced protein carbonyl formation and lipid peroxidation in blood platelets and plasma exposed to peroxynitrite. This suggests that these compounds may have potential antioxidant properties, potentially contributing to the prevention of diseases related to oxidative stress.
Antioxidant Power From Nature's Bounty
This research exemplifies the untapped potential of natural compounds like garcinol and guttiferone K, highlighting their potential to combat oxidative stress. It reminds us that a vast desert of natural remedies awaits exploration, offering promising solutions to various health challenges.
Dr. Camel's Conclusion
This study provides a fascinating glimpse into the potential of natural compounds as antioxidants. Garcinol and guttiferone K emerge as promising candidates for further investigation, offering a path towards the development of novel antioxidant-based therapies.
Date :
- Date Completed 2010-02-18
- Date Revised 2017-11-16
Further Info :
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