Drug metabolism for the perplexed medicinal chemist.

Author: TestaBernard

Paper Details 
Original Abstract of the Article :
Two related and significant issues may elicit perplexity in medicinal chemists and are discussed here. First, a broad presentation of the pharmacological and toxicological consequences of drug metabolism should justify the significance of drug metabolism and serve as an incentive to further study. W...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/cbdv.200900052

データ提供:米国国立医学図書館(NLM)

Drug Metabolism: A Perplexing Desert of Chemical Transformations

Drug metabolism, the complex process by which the body transforms medications, is like a vast and intricate desert landscape. It's a world of chemical reactions, enzymes, and pathways, all working together to modify drugs and prepare them for elimination. This article delves into the complexities of drug metabolism, exploring the pharmacological and toxicological consequences of these transformations. The author discusses the concept of prodrugs, which are inactive medications that become activated through metabolism, and the potential for drug metabolism to generate toxic metabolites. This article provides a valuable overview of the intricate world of drug metabolism, highlighting its significance in drug development and patient care.

Navigating the Desert of Drug Metabolism: A Guide for Medicinal Chemists

This article serves as a valuable guide for medicinal chemists navigating the complex desert landscape of drug metabolism. It provides a comprehensive overview of the various pathways and enzymes involved in drug transformation, highlighting the potential pharmacological and toxicological consequences. It's like having a compass in the desert, guiding chemists to understand the intricate workings of drug metabolism and develop safer and more effective medications.

Understanding the Desert's Secrets: The Importance of Drug Metabolism

Drug metabolism is a critical process that can profoundly influence the efficacy and safety of medications. This article sheds light on the intricacies of this process, providing valuable insights for both chemists and healthcare professionals. It's like uncovering a hidden oasis in the desert, revealing a wealth of knowledge about the complex interplay between drugs and the human body.

Dr. Camel's Conclusion

Drug metabolism, like a vast and complex desert, holds many secrets. This article provides a valuable exploration of this intricate process, highlighting its importance in understanding drug efficacy and safety. By delving deeper into the desert of drug metabolism, we can gain a better understanding of how medications interact with the human body and develop safer and more effective treatments.

Date :
  1. Date Completed 2010-02-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19937836

DOI: Digital Object Identifier

10.1002/cbdv.200900052

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.