The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Author: AmmiratiMario, AndrewsDavid W, AsherAnthony L, BurriStuart H, CobbsCharles S, GasparLaurie E, KalkanisSteven N, KondziolkaDouglas, LinskeyMark E, LoefflerJay S, McDermottMichael, MehtaMinesh P, MikkelsenTom, MorrisRachel E, OlsonJeffrey J, PaleologosNina A, PatchellRoy A, RobinsonPaula D, RykenTimothy C

Paper Details 
Original Abstract of the Article :
QUESTION: Should patients with newly-diagnosed metastatic brain tumors undergo open surgical resection versus whole brain radiation therapy (WBRT) and/or other treatment modalities such as radiosurgery, and in what clinical settings? TARGET POPULATION: These recommendations apply to adults with a n...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808517/

データ提供:米国国立医学図書館(NLM)

Navigating the Treatment Landscape for Brain Metastases: A Comprehensive Review

This research delves into the complex world of [cancer treatment] and specifically examines the role of [whole brain radiation therapy (WBRT)] in managing [newly diagnosed brain metastases]. The authors conducted a [systematic review] of existing evidence to provide an evidence-based clinical practice guideline for the treatment of [single brain metastasis]. They analyzed the effectiveness of [surgical resection] alone versus [surgical resection] combined with [WBRT], as well as the role of [stereotactic radiosurgery (SRS)] in treating [brain metastases]. The researchers found that [surgical resection] followed by [WBRT] leads to better [tumor control] compared to [surgical resection] alone. They also found that [surgical resection] with [WBRT] and [SRS] with or without [WBRT] are both effective treatment strategies with comparable [survival rates].

The Power of Multimodal Treatment: Combining Therapies for Optimal Outcomes

This review highlights the importance of considering a multimodal approach to treating [brain metastases]. The researchers found that combining [surgical resection] with [WBRT] or [SRS] significantly improves [tumor control] and [survival] compared to [surgical resection] alone. This underscores the value of considering a tailored approach to treatment based on individual patient characteristics and tumor characteristics.

Making Informed Decisions: Empowering Patients in Treatment Choices

This research provides valuable information for patients diagnosed with [brain metastases] and their families. It helps patients understand the different [treatment options] available, the potential benefits and risks associated with each, and the importance of consulting with their physician to develop a personalized treatment plan. It emphasizes the importance of close monitoring for any signs of [disease progression] and timely interventions to ensure optimal [treatment outcomes].

Dr.Camel's Conclusion

This review provides a valuable roadmap for navigating the treatment landscape for [brain metastases]. By summarizing existing evidence and providing clinical practice guidelines, the authors have created a valuable resource for both clinicians and patients. Just as a camel navigates the shifting sands of the desert, patients with [brain metastases] can confidently navigate their treatment journey with the help of this research.

Date :
  1. Date Completed 2010-03-24
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

19960231

DOI: Digital Object Identifier

PMC2808517

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.