Patterns of combination therapy with alefacept for the treatment of psoriasis in Canada in the AWARE study.

Author: BissonnetteRobert, LandellsIan, LuiHarvey, PappKim, SearlesGordon, ShearNeil H

Paper Details 
Original Abstract of the Article :
BACKGROUND: Evidence from clinical trials supports the use of alefacept for the treatment of patients with chronic plaque psoriasis, either as monotherapy or combined with other treatment modalities. OBJECTIVE: AWARE (Amevive Wisdom Acquired from Real-World Evidence) is a multicenter, observational...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.2310/7750.2009.00031

データ提供:米国国立医学図書館(NLM)

Alefacept: A Combination Therapy for Psoriasis in Canada

This study delves into the world of [psoriasis treatment] and explores the use of alefacept, a medication known to be effective in treating chronic plaque psoriasis. The authors present data from the AWARE study, a large observational registry of psoriasis patients in Canada, focusing on the use of alefacept in combination therapy. The study demonstrates that alefacept is frequently used in combination with other antipsoriatic therapies, particularly topical treatments, systemic agents, and phototherapy. The study further reveals that alefacept often allows patients to reduce or discontinue the use of these concomitant therapies, suggesting a significant benefit in terms of reducing the overall treatment burden. This study provides valuable insights into the real-world application of alefacept and its potential to improve psoriasis management.

Real-World Evidence Supports the Use of Alefacept in Combination Therapy

The AWARE study reveals that alefacept is commonly used alongside other antipsoriatic therapies in a real-world setting. This is a testament to its effectiveness and versatility in managing psoriasis. The data also suggests that alefacept might allow patients to reduce or even discontinue other therapies, which could lead to fewer side effects and better overall patient well-being. The study's findings are a significant step forward in understanding the role of alefacept in psoriasis management.

Navigating Psoriasis Treatment with Alefacept

Psoriasis, with its unpredictable nature, can be a challenging condition to manage. The findings of this study offer valuable information for patients seeking effective treatment options. Alefacept, in combination with other therapies, may be a promising approach to managing psoriasis and reducing the need for more intensive treatments. It's important to remember that every individual is unique, and the best treatment approach should be determined in consultation with a healthcare professional.

Dr.Camel's Conclusion

The AWARE study provides a glimpse into the real-world use of alefacept in psoriasis management, revealing its potential as a valuable addition to existing treatment options. It's like discovering a hidden oasis in a vast desert, offering a new and potentially less burdensome approach to managing psoriasis. This research is a testament to the importance of ongoing research in finding effective and safe treatments for chronic conditions like psoriasis.

Date :
  1. Date Completed 2010-04-29
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20053325

DOI: Digital Object Identifier

10.2310/7750.2009.00031

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.