A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood.

Author: BlizardRobert, BuszewiczMarta J, OsborneDebbie, RavenPeter W, SerfatyMarc Antony

Paper Details 
Original Abstract of the Article :
Sleep disturbance is common in major depressive disorder (MDD), and is often characterized by early-morning waking. Melatonin is a hypnotic and synchronizes circadian rhythms. It may also be an antidepressant. The melatonin agonists, ramelteon and agomelatine, have hypnotic and antidepressant proper...See full text at original site
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引用元:
https://doi.org/10.1097/YIC.0b013e32832c260b

データ提供:米国国立医学図書館(NLM)

Melatonin: A Potential Oasis for Sleep and Mood

This research explores the intersection of psychiatry and sleep medicine, examining the potential benefits of melatonin for treating both sleep disturbance and depressed mood in individuals with major depressive disorder (MDD). The study, using a randomized, double-blind, placebo-controlled design, found that melatonin had a positive effect on sleep and mood, suggesting that it could be a valuable tool for managing these common symptoms of MDD.

Melatonin: A Light in the Desert of Depression

This study suggests that melatonin could be a promising treatment for the sleep and mood disturbances associated with depression. It's like discovering a new oasis in the desert of depression, offering relief from the symptoms and potentially improving overall well-being.

Managing Depression: A Holistic Approach

This research highlights the importance of addressing both sleep and mood disturbances in the treatment of depression. Melatonin could be a valuable tool for managing these symptoms, but other treatments, such as psychotherapy or antidepressants, may also be necessary. It's like navigating a complex desert, where a combination of resources and strategies are needed to overcome the challenges of depression.

Dr.Camel's Conclusion

This study provides encouraging evidence for the potential benefits of melatonin in treating sleep and mood disturbances in individuals with major depressive disorder. It underscores the importance of a holistic approach to managing depression, addressing both the physical and emotional aspects of this complex condition. This research is a step forward in the search for more effective and tolerable treatment options for those living with depression.

Date :
  1. Date Completed 2010-07-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

20195158

DOI: Digital Object Identifier

10.1097/YIC.0b013e32832c260b

Related Literature

SNS
PICO Info
in preparation
Languages

English

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