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[Local treatment of a chronic anal fissure with diltiazem vs. nitroglycerin. A comparative study].

Author: Ali-MahmoudIsmail, García-CoretM José, PucheJosé J, RoigJosé V, VillalbaFrancisco L

English AbstractA summary of a research paper/publication written in English for a wider audience.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Smooth muscle relaxant drugs, like diltiazem and nitroglycerin, offered more symptomatic relief than traditional measures for chronic anal fissure (CAF) but did not achieve a higher cure rate. Topical diltiazem was better tolerated than nitroglycerin.
Paper Details　
Original Abstract of the Article :
AIM: To assess the value of using smooth muscle relaxants drugs and assess the results of the topical use of 2% diltiazem as an alternative to 0.2% nitroglycerin in the treatment of chronic anal fissure (CAF). METHODS: Review of the CAF contained in a prospectively collected database of anal fissur...See full text at original site
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引用元：
https://doi.org/10.1016/j.ciresp.2009.12.013

データ提供：米国国立医学図書館（NLM）

Diltiazem vs. Nitroglycerin: A Comparative Study for Chronic Anal Fissure Treatment

This research compares the effectiveness of two smooth muscle relaxants, diltiazem and nitroglycerin, in the treatment of chronic anal fissure (CAF). The study, conducted prospectively, analyzed the outcomes of patients treated with standard measures, nitroglycerin ointment, or topical diltiazem. The results indicated that both diltiazem and nitroglycerin provided symptomatic relief, but diltiazem was better tolerated and had fewer side effects.

Finding Relief from Anal Fissures: A Comparison of Treatments

The study's findings suggest that topical diltiazem may be a preferred treatment option for CAF, offering comparable symptom relief with fewer side effects compared to nitroglycerin. This is like choosing the right camel for a long journey through the desert; a camel with fewer quirks and greater resilience is likely to provide a smoother experience.

Anal Fissures: Seeking Professional Help

If you are experiencing symptoms of anal fissures, it's crucial to consult a healthcare professional. They can provide a proper diagnosis and recommend the most appropriate treatment for your specific condition. Remember, just as a camel caravan relies on its guide to navigate treacherous terrain, you should seek guidance from a medical expert for your health concerns.

Dr. Camel's Conclusion

This study highlights the potential of diltiazem as an effective and well-tolerated treatment for chronic anal fissures. It's a valuable tool for easing discomfort and improving quality of life for patients suffering from this condition. Just as a camel carries its burden with grace, diltiazem can provide a gentle and effective way to relieve the discomfort of anal fissures.
Date :
  1. Date Completed 2010-08-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

20206340

DOI: Digital Object Identifier

10.1016/j.ciresp.2009.12.013

SNS
PICO Info
in preparation
Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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