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Combined albendazole and amphotericin B against Echinococcus multilocularis in vitro.
Author: BeislerTaro, KernPeter, ReuterStefan
Original Abstract of the Article :
Benzimidazoles, namely albendazole (ABZ) and mebendazole, are the only drugs licensed for the treatment of inoperable alveolar echinococcosis. In addition, amphotericin B (AMB) has shown effect against Echinococcus multilocularis as salvage treatment in humans. Both benzimidazoles and AMB are only p...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.actatropica.2010.04.009
データ提供:米国国立医学図書館(NLM)
Combined Albendazole and Amphotericin B Against Echinococcus multilocularis
This research delves into the challenging world of parasitic infections, a territory as vast and complex as a sprawling desert. The researchers investigated the potential of combining albendazole, a benzimidazole drug, with amphotericin B, an antifungal medication, to treat alveolar echinococcosis, a parasitic infection that can be as debilitating as a sandstorm sweeping through a desert oasis.Combating the Desert Parasite: Exploring a Combined Therapy for Echinococcosis
The study explored the effects of combining these two drugs on Echinococcus multilocularis larvae in an in vitro model. This is like studying the effects of different desert plants on a specific type of desert insect, hoping to find a combination that can effectively control its population. The researchers found that sequential application of albendazole and amphotericin B was more effective than amphotericin B alone, offering a potential strategy for managing this challenging infection.Protecting the Oasis from the Desert Parasite: A Multifaceted Approach to Treatment
This research underscores the need for a multi-pronged approach to treating parasitic infections. The study highlights the potential benefits of combining different medications to target specific aspects of the parasite's lifecycle, increasing the effectiveness of treatment and minimizing side effects. This is like using a variety of tools and strategies to combat a desert pest, ensuring the long-term health and vitality of the oasis.Dr.Camel's Conclusion
This research highlights the importance of ongoing research in the field of parasitology. Just as a desert explorer must constantly adapt to the changing environment, researchers must continue to explore new and innovative ways to combat parasitic infections, protecting vulnerable populations from these devastating diseases.Date :
- Date Completed 2010-09-20
- Date Revised 2013-11-21
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