Osteonecrosis of the jaw induced by clodronate, an alkylbiphosphonate: case report and literature review.

Author: CrépinSabrina, LarocheMarie-Laure, MerleLouis, SarryBernard

Paper Details 
Original Abstract of the Article :
PURPOSE: To report on a case of osteonecrosis of the jaw (ONJ) in a patient treated with clodronate, an alkylbiphosphonate, and to draw attention to the risk of ONJ following treatment with all biphosphonates, whether they are alkyl- or amino-biphosphonates. CASE REPORT: Beginning at age 58 years, ...See full text at original site
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引用元:
https://doi.org/10.1007/s00228-010-0822-5

データ提供:米国国立医学図書館(NLM)

Clodronate-Induced Osteonecrosis of the Jaw: Navigating the Desert of Unintended Consequences

Imagine a vast desert where clodronate, a type of bisphosphonate medication, is like a powerful tool used to strengthen bones and prevent fractures. However, like any powerful tool, clodronate can have unintended consequences, leading to a serious complication called osteonecrosis of the jaw (ONJ).

This case report presents a rare instance of ONJ in a patient treated with clodronate, highlighting the importance of recognizing the potential risks associated with this medication. It's like discovering a hidden danger lurking beneath the surface of a seemingly safe desert, prompting us to reconsider our approach to using this powerful tool.

The Importance of Vigilance

This case report emphasizes the importance of careful monitoring and proactive management when prescribing bisphosphonates, especially for long-term use. Like a wise traveler navigating a desert, we need to be vigilant and aware of the potential pitfalls, ensuring the safety and well-being of those entrusted to our care.

Health Implications and Practical Tips

The findings of this case report provide a valuable warning for healthcare providers, highlighting the importance of understanding the potential risks associated with bisphosphonate therapy. It encourages us to engage in open and honest communication with patients, discussing potential side effects and developing personalized treatment plans that minimize risks.

Dr.Camel's Conclusion

This case report serves as a reminder that the desert of medicine is vast and unpredictable, and even seemingly beneficial medications can have unintended consequences. By remaining vigilant and embracing a proactive approach to managing these potential risks, we can improve the safety and well-being of those entrusted to our care.

Date :
  1. Date Completed 2010-07-26
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20437036

DOI: Digital Object Identifier

10.1007/s00228-010-0822-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

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