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Beneficial effects of loxapine on agitation and breathing patterns during weaning from mechanical ventilation.

Author: BertrandFabrice, ChevrelGuillaume, DreyfussDidier, HurelDominique, MargetisDimitri, RicardJean-Damien, SztrymfBenjamin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Loxapine was safe and effective in treating agitation in mechanically ventilated patients, improving respiratory physiologic parameters and facilitating the weaning process.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Interruption of sedation during weaning from mechanical ventilation often leads to patient agitation because of withdrawal syndrome. We tested the short-term efficacy and tolerance of loxapine in this situation. METHODS: Nineteen mechanically ventilated patients with marked agitation ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911718/

データ提供：米国国立医学図書館（NLM）

Loxapine: A Potential Solution for Agitation During Weaning

Weaning from mechanical ventilation can be a challenging process, often accompanied by agitation and discomfort. This research explores the use of loxapine, an antipsychotic medication, to manage agitation during weaning. The authors administered loxapine to mechanically ventilated patients experiencing agitation, observing a significant reduction in agitation levels and improved respiratory function. The results suggest that loxapine could be a valuable tool for managing agitation during weaning from mechanical ventilation, making the process smoother and more comfortable for patients.

Loxapine Offers Hope for Managing Agitation During Weaning

The research suggests that loxapine could be an effective treatment for agitation during weaning from mechanical ventilation. This finding could lead to improved patient comfort and faster recovery times.

Addressing the Challenges of Weaning from Mechanical Ventilation

Weaning from mechanical ventilation can be a complex and stressful process for patients. This research highlights the importance of addressing the challenges associated with weaning, such as agitation, to improve patient outcomes.

Dr. Camel's Conclusion

This research suggests that loxapine could be a valuable tool for managing agitation during weaning from mechanical ventilation, improving patient comfort and potentially facilitating a smoother recovery process.
Date :
  1. Date Completed 2011-01-06
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20459867

DOI: Digital Object Identifier

PMC2911718

Related Literature

Article Analysis
・Effects of loxapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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