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The complex clinical picture of presumably allergic side effects to cytostatic drugs: symptoms, pathomechanism, reexposure, and desensitization.

Author: PaganiMauro

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The use of cytotoxic agents in cancer treatment is associated with hypersensitivity reactions, which are a significant problem for clinicians. Platinum compounds, L-asparaginase, taxanes, procarbazine, and epipodophyllotoxins are particularly prone to causing these reactions.
Paper Details　
Original Abstract of the Article :
The number of drugs used for the treatment of different types of cancers is constantly increasing and actually exceeds 100 distinct chemical formulations. The use of most cytotoxic agents is associated with potential hypersensitivity reactions, and the constant increase of their administration has c...See full text at original site
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引用元：
https://doi.org/10.1016/j.mcna.2010.03.002

データ提供：米国国立医学図書館（NLM）

The Shifting Sands of Cancer Treatment: Allergic Reactions to Cytostatics

The battle against cancer is a challenging journey, akin to traversing a vast and unforgiving desert. This article, published in the journal Annals of Oncology, explores the complex clinical picture of allergic reactions to cytostatic drugs, medications used to treat cancer. These reactions, like treacherous sandstorms, can disrupt the treatment process and pose significant challenges for both patients and clinicians.

A Desert of Uncertainty: Allergic Reactions to Cytostatic Drugs

The authors discuss the different types of hypersensitivity reactions associated with cytostatic drugs, highlighting the wide range of possibilities, like the diverse flora and fauna of a desert landscape. They explain the different mechanisms behind these reactions, comparing it to unraveling the mysteries of a desert ecosystem, emphasizing the need for a multidisciplinary approach to manage patients with potential allergies to these crucial medications.

Navigating the Risks: Managing Allergic Reactions

This article, like a compass guiding travelers through a desert, offers valuable insights into the management of allergic reactions to cytostatic drugs. The authors underscore the importance of identifying and managing these reactions, ensuring the treatment journey is as safe and effective as possible.

Dr. Camel's Conclusion

This article serves as a reminder that the desert of cancer treatment is fraught with challenges. While cytostatic drugs offer hope for patients, they can also trigger unpredictable allergic reactions. Careful monitoring and a multidisciplinary approach are essential in managing these risks, ensuring the path to recovery is as smooth as possible.

Date :
  1. Date Completed 2010-09-10
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20609866

DOI: Digital Object Identifier

10.1016/j.mcna.2010.03.002

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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