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Prasugrel: a novel platelet ADP P2Y(12) receptor antagonist.
Author: FareedJawed, JeskeWalter P, MousaShaker A
Original Abstract of the Article :
Novel adenosine diphosphate (ADP) P2Y(12) antagonists such as prasugrel, ticagrelor, cangrelor, and elinogrel are in various phases of clinical development. These ADP P2Y(12) antagonists have advantages over clopidogrel ranging from faster onset to greater and less variable inhibition of platelet fu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/978-1-60761-803-4_8
データ提供:米国国立医学図書館(NLM)
Prasugrel: A Novel Antiplatelet Agent
This research delves into the fascinating world of antiplatelet therapy, introducing prasugrel, a novel third-generation oral thienopyridine that specifically targets the platelet ADP P2Y12 receptor. The researchers highlight prasugrel's advantages over clopidogrel, a commonly used antiplatelet medication, including faster onset of action, greater and less variable inhibition of platelet function, and improved antithrombotic effects.
Prasugrel: A Potent Antiplatelet Agent with Promise
The researchers found that prasugrel provided more rapid and consistent platelet inhibition compared to clopidogrel, demonstrating its potential to prevent ischemic events in patients undergoing percutaneous coronary intervention (PCI). However, they also noted an increased risk of bleeding associated with prasugrel, highlighting the need for careful patient selection and monitoring.
Balancing Benefits and Risks in Antiplatelet Therapy
This research underscores the need for a careful balance between the benefits and risks of antiplatelet therapy. Prasugrel's potent antiplatelet effects offer promise for preventing cardiovascular events, but its increased bleeding risk requires careful consideration and management.
Dr. Camel's Conclusion
This study provides a comprehensive overview of prasugrel, a novel antiplatelet agent with potential benefits for cardiovascular health. The researchers' findings highlight the importance of ongoing research in the development of new antiplatelet medications, ensuring that we have effective and safe treatment options for patients with cardiovascular disease.
Date :
- Date Completed 2010-10-08
- Date Revised 2015-11-19
Further Info :
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English
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