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Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents.

Author: BrownM B, EvansC R G, JonesS A, KhengarR H, TraynorM J, TurnerR B

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A novel permeation enhancer system enhanced the delivery of terbinafine through human nail samples in vitro, suggesting potential for a topical treatment of nail fungal infections.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: The aim of this study was to demonstrate the effect of a novel permeation enhancer system using two existing marketed nail lacquers and the delivery of terbinafine through human nail samples in vitro. METHODS: Initially a modified Franz cell was used, where sections of human nail serve ...See full text at original site
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引用元：
https://doi.org/10.1211/jpp.62.06.0009

データ提供：米国国立医学図書館（NLM）

Unlocking the Potential of Nail Fungus Treatment

This research investigates the potential of a novel permeation enhancer system to improve the delivery and efficacy of antifungal agents for nail infections. The study focuses on terbinafine, a commonly used antifungal medication, and explores its effectiveness when delivered through the nail using a new permeation enhancing system.

Delivering Antifungal Solutions: A New Approach

The study demonstrates that the novel permeation enhancing system significantly increases the permeation of antifungal agents, including terbinafine, through human nail sections. This could potentially lead to more effective treatment of nail infections, as the enhanced delivery system could deliver a higher concentration of antifungal agents directly to the site of infection.

Targeting Nail Infections: A New Frontier

Think of a nail infection as a stubborn cactus thorn embedded in your foot. This research explores new ways to deliver the right medicine to the root of the problem, offering a more effective approach to treating nail infections. The novel permeation enhancer system could be a game-changer in the fight against these tenacious fungal infections.

Dr.Camel's Conclusion

This research showcases a promising new approach to treating nail infections. By enhancing the delivery of antifungal medications directly to the affected area, this novel system could offer a more effective and targeted treatment approach. It's like finding a hidden oasis in the desert, offering relief and healing for those struggling with persistent nail infections.

Date :
  1. Date Completed 2010-10-26
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20636860

DOI: Digital Object Identifier

10.1211/jpp.62.06.0009

Related Literature

Article Analysis
・Side Effects of terbinafine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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