Calcium antagonists, diltiazem and nifedipine, protect broilers against low temperature-induced pulmonary hypertension and pulmonary vascular remodeling.

Author: GaoMingyu, GuoYuming, QiaoJian, YangYing

Paper Details 
Original Abstract of the Article :
This study was designed to determine whether calcium antagonists, diltiazem and nifedipine, can depress low temperature-induced pulmonary hypertension (PH) in broilers (also known as ascites) and to characterize their efficacy on hemodynamics and pulmonary artery function. Chicks were randomly alloc...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1740-0929.2010.00762.x

データ提供:米国国立医学図書館(NLM)

Calcium Antagonists for Pulmonary Hypertension in Broilers

Pulmonary hypertension (PH), a serious condition affecting the lungs, can be exacerbated by environmental factors. This research investigates the potential of calcium antagonists, diltiazem and nifedipine, to prevent low temperature-induced PH in broilers, a common poultry breed. The authors conducted a study comparing the effects of diltiazem and nifedipine on hemodynamics and pulmonary artery function in broilers exposed to low temperatures. This study offers valuable insights into the potential of calcium antagonists as preventive measures for PH in poultry.

Diltiazem Shows Promise for Preventing PH in Broilers

The study found that diltiazem effectively protected broilers from low temperature-induced PH and vascular remodeling. While nifedipine showed some early protective effects, it was not as effective as diltiazem in preventing the development of PH in the long term. This information highlights the potential of diltiazem as a promising preventive strategy for PH in poultry.

Understanding Pulmonary Hypertension in Poultry

This research underscores the importance of environmental factors in influencing the development of PH in poultry. The findings suggest that calcium antagonists, particularly diltiazem, may play a role in preventing PH in broilers exposed to low temperatures. This study encourages further research to optimize the use of calcium antagonists in poultry management practices.

Dr.Camel's Conclusion

Imagine a camel seeking shelter from the scorching desert sun, seeking relief from the oppressive heat. This research is like a cool breeze, offering a potential solution to the challenge of low temperature-induced PH in broilers. Diltiazem, a calcium antagonist, emerges as a promising preventive measure, reminding us that a proactive approach to managing environmental factors can contribute to the health and well-being of our feathered friends.

Date :
  1. Date Completed 2010-12-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

20662820

DOI: Digital Object Identifier

10.1111/j.1740-0929.2010.00762.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.