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A validated method for simultaneous screening and quantification of twenty-three benzodiazepines and metabolites plus zopiclone and zaleplone in whole blood by liquid-liquid extraction and ultra-performance liquid chromatography- tandem mass spectrometry.
Author: HermanssonSigurd, LinnetKristian, SimonsenKirsten Wiese, SteentoftAnni
Original Abstract of the Article :
An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for detection of 23 benzodiazepines and related compounds in whole blood was developed and validated. The method is used for screening and quantitation of benzodiazepines in whole blood received from autopsy case...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1093/jat/34.6.332
データ提供:米国国立医学図書館(NLM)
Benzodiazepine Detection in Blood: A Desert Oasis of Forensic Science
Benzodiazepines, a class of drugs commonly used to treat anxiety and insomnia, are like a mirage in the desert of pharmaceutical research. This study, conducted like a meticulous desert expedition, developed a method for detecting and quantifying 23 benzodiazepines and their metabolites in blood samples. They used a cutting-edge technique called ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) to achieve accurate and reliable results. The method was validated using blood samples from drug-free volunteers, ensuring its accuracy and reliability. This study, as clear as a desert sky at sunset, provides a valuable tool for forensic scientists and medical professionals involved in drug testing and toxicology.Benzodiazepine Detection: A Desert Oasis of Accuracy
This study, as vast as the desert itself, presents a fully validated method for detecting and quantifying 23 benzodiazepines in blood samples. The findings, as clear as a desert well after a long trek, offer a valuable tool for forensic scientists and medical professionals involved in drug testing and toxicology.Benzodiazepine Testing: Navigating the Desert Landscape
Benzodiazepine use, whether for therapeutic or non-therapeutic reasons, can have significant implications. This study, like a well-marked trail in the desert, provides a valuable tool for accurate and reliable testing of benzodiazepines in blood samples. This information is essential for forensic investigations, medical diagnosis, and patient safety.Dr. Camel's Conclusion
This study provides a valuable tool for the detection and quantification of benzodiazepines in blood samples. The method, as clear as a desert sky at dawn, is crucial for forensic science, medical toxicology, and ensuring patient safety.Date :
- Date Completed 2010-11-04
- Date Revised 2019-12-10
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