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[Therapeutic drug monitoring of 6-thioguanine nucleotides in inflammatory bowel disease: interest and limits].
Author: , BoulieuRoselyne, FonroseXavier, JourdilNicole, Stanke-LabesqueFrançoise
Original Abstract of the Article :
Azathioprine, 6-mercaptopurine, and 6-thioguanine are immunosuppressive drugs indicated in the prevention of graft rejection, and treatment of auto-immune disease or inflammatory bowel disease. Their anti-nucleotidic properties are also used for the treatment of acute leukaemia. Their metabolism inv...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/20699068
データ提供:米国国立医学図書館(NLM)
Therapeutic Drug Monitoring of 6-Thioguanine Nucleotides in Inflammatory Bowel Disease: A Balancing Act
The management of inflammatory bowel disease (IBD) is a delicate balancing act, much like navigating a desert landscape where every step must be carefully considered. This research explores the use of therapeutic drug monitoring (TDM) to optimize the treatment of IBD with thiopurine drugs, medications that can effectively manage the disease but also carry potential side effects. The authors delve into the role of TDM in ensuring appropriate dosing and minimizing the risk of adverse effects, providing a valuable tool for clinicians and patients alike.
The Importance of Therapeutic Drug Monitoring in IBD
This research, like a carefully constructed map of a desert region, highlights the importance of TDM in managing IBD patients treated with thiopurine drugs. The authors emphasize the need to balance the therapeutic benefits of these medications with the potential for toxicity. TDM can help clinicians tailor dosage to individual patients, ensuring they receive the optimal therapeutic effect while minimizing the risk of side effects. This approach, like a cool desert breeze, can offer a more comfortable and effective treatment experience for patients.
Navigating IBD Treatment with TDM
As you navigate the desert of IBD management, remember that open communication with your doctor is essential. Discuss your concerns, potential treatment options, and any side effects you experience. Like a wise camel, be proactive in managing your health and seeking professional guidance when needed. TDM can be a valuable tool in this journey, helping you and your doctor make informed decisions about your treatment and ensure the best possible outcome.
Dr.Camel's Conclusion
This research emphasizes the vital role of TDM in optimizing thiopurine therapy for IBD patients. By carefully monitoring drug levels and adjusting dosages accordingly, clinicians can ensure that patients receive the full benefits of these medications while minimizing the risk of adverse effects. It's a reminder that even in the vast and complex landscape of IBD management, we have tools and strategies to help patients navigate this challenging journey and achieve optimal health.
Date :
- Date Completed 2010-10-25
- Date Revised 2013-11-21
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