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Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate.

Author: GowJames A, KlierSharon M, McCueShannon L, McNamaraTimothy R, SalapatekAnne Marie F, WilliamsJon I

Evaluation StudyResearch that systematically evaluates the effectiveness of a particular program or policy. It measures its outcomes and provides important information for future decision-making.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Bepotastine besilate, a second-generation antihistamine, demonstrated favorable pharmacokinetic, pharmacologic, safety, and antihistamine properties in non-clinical studies. It also showed additional anti-allergic activity beyond histamine H1 receptor antagonism.
Paper Details　
Original Abstract of the Article :
SCOPE: The purpose of this review is to examine published non-clinical literature on the antihistamine bepotastine besilate, including pharmacokinetic and pharmacologic properties. METHODS: Standard literature searches using diverse databases were used to find articles on bepotastine besilate publi...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2010.486753

データ提供：米国国立医学図書館（NLM）

Bepotastine Besilate: A Desert Oasis for Allergy Relief

Allergies, like pesky desert sandstorms, can cause a range of uncomfortable symptoms, including sneezing, itchy eyes, and runny nose. This study explores the non-clinical properties of bepotastine besilate, an antihistamine drug, examining its safety and effectiveness in treating allergic reactions.

Bepotastine Besilate: A Safe and Effective Antihistamine

The study found that bepotastine besilate exhibits a selective affinity for histamine H1 receptors, blocking the release of histamine, a chemical involved in allergic reactions. It also demonstrates additional anti-allergic properties, like stabilizing mast cells and inhibiting eosinophilic infiltration. It's like finding a well-stocked oasis in the desert, offering relief from the harsh desert conditions.

Navigating the Allergy Desert

This study highlights the potential of bepotastine besilate as a safe and effective antihistamine, offering a promising solution for those seeking relief from allergy symptoms. It's like having a reliable camel caravan to help you navigate the desert safely and comfortably.

Dr. Camel's Conclusion

This research provides valuable insights into the properties of bepotastine besilate, a promising drug for treating allergic reactions. It's a reminder that the desert of allergies is a challenging terrain, but finding the right tools and treatments can make the journey a lot more manageable.
Date :
  1. Date Completed 2011-02-09
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

20735291

DOI: Digital Object Identifier

10.1185/03007995.2010.486753

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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