Efficacy and safety of single doses of intramuscular ketorolac tromethamine compared with meperidine for postoperative pain.

Author: BradleyR, CherryC, SarnquistF H, StanskiD R, YeeJ P

Paper Details 
Original Abstract of the Article :
Ketorolac tromethamine, a potent nonnarcotic prostaglandin synthetase-inhibiting analgesic, was compared with meperidine for relief of moderate to severe postoperative pain. In a double-blind, randomized study, 125 patients received single intramuscular doses of ketorolac 30 or 90 mg or meperidine 5...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2082312

データ提供:米国国立医学図書館(NLM)

Pain Relief: A Journey Through the Desert

Postoperative pain, a common experience that can significantly impact recovery, is the focus of this double-blind, randomized study. The researchers embarked on a journey to compare the effectiveness of single intramuscular doses of ketorolac, a potent nonnarcotic prostaglandin synthetase-inhibiting analgesic, with meperidine, a traditional opioid analgesic, for the relief of moderate to severe postoperative pain. The study involved 125 patients who received either ketorolac (30 or 90 mg) or meperidine (50 or 100 mg). The results of this investigation revealed that both doses of ketorolac demonstrated a significantly longer duration of analgesic effect compared to meperidine, while exhibiting comparable onset and peak analgesic effects. Importantly, ketorolac was associated with a reduced risk of respiratory depression, a common side effect of opioids. This study offers a promising alternative for postoperative pain management, potentially leading to a more comfortable recovery experience for patients.

A New Oasis in the Desert of Postoperative Pain

The findings suggest that ketorolac could be a valuable tool for managing postoperative pain, offering a prolonged analgesic effect with reduced risk of respiratory depression. This could potentially lead to a more comfortable and expedited recovery process for patients, allowing them to navigate the desert of postoperative pain with greater ease and speed.

Navigating the Desert with Confidence

While the study suggests the potential benefits of ketorolac, it is crucial to consult with a healthcare professional to determine the most appropriate pain management strategy for individual needs. As we continue to explore the vast desert of postoperative pain management, we can hopefully discover more effective and personalized treatments, ultimately leading to a more comfortable and seamless recovery experience for all patients.

Dr.Camel's Conclusion

This research sheds light on the potential of ketorolac as a valuable tool for postoperative pain management, offering a longer duration of pain relief with reduced risk of respiratory depression. This discovery signifies a significant stride in the ongoing quest to improve patient comfort and expedite recovery, leading us closer to a more manageable and comfortable landscape for those navigating the desert of postoperative pain.

Date :
  1. Date Completed 1991-05-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2082312

DOI: Digital Object Identifier

2082312

Related Literature

SNS
PICO Info
in preparation
Languages

English

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