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Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension.

Author: ChrysantSteven G, DattaniDan, HoppeUta C, MurrayAlexander V, PatelSamir, RitterShannon, ZhangJack

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Aliskiren/valsartan combination therapy provides effective blood pressure control and is well-tolerated in patients with hypertension.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To assess the long-term safety and antihypertensive efficacy of aliskiren/valsartan 300/320 mg combination. METHODS: This was a 54-week, multicenter, open-label study (core phase), followed by a 26-week extension phase. Efficacy variables were change in msDBP and msSBP from baseline to e...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2010.528282

データ提供：米国国立医学図書館（NLM）

Long-Term Safety and Efficacy of Aliskiren and Valsartan Combination with or without the Addition of HCT in Patients with Hypertension

In the world of [cardiology], managing [hypertension] is crucial for preventing cardiovascular disease. This study explores the long-term safety and efficacy of a combination of [aliskiren] and [valsartan] with or without [hydrochlorothiazide (HCT)] for treating [hypertension].

Aliskiren and Valsartan Combo May be Effective for Hypertension

This study found that the combination of [aliskiren] and [valsartan] was effective in reducing [blood pressure] and was generally well-tolerated. The addition of [HCT] further improved [blood pressure control] in patients who did not achieve adequate control with the combination alone.

Managing Hypertension

If you have [hypertension], it’s important to work closely with your doctor to manage your condition effectively. This study provides valuable information about potential treatment options, including the combination of [aliskiren] and [valsartan].

Dr.Camel's Conclusion

This research reminds us that the desert of [cardiology] is a landscape of ongoing exploration. We are constantly discovering new ways to manage [hypertension], and this study provides valuable insights for physicians and patients alike.
Date :
  1. Date Completed 2011-03-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21062137

DOI: Digital Object Identifier

10.1185/03007995.2010.528282

Related Literature

Article Analysis
・Side Effects of aliskiren
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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