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Combined androgen blockade for prostate cancer: review of efficacy, safety and cost-effectiveness.

Author: AkazaHideyuki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Combined androgen blockade (CAB) is a treatment for prostate cancer that involves using an antiandrogen plus castration. This review discusses the feasibility of CAB with bicalutamide for the treatment of prostate cancer.
Paper Details　
Original Abstract of the Article :
A standard treatment for advanced prostate cancer is androgen deprivation by surgical or medical castration. In theory, however, combined androgen blockade (CAB) with an antiandrogen plus castration should be more effective because castration alone does not completely eliminate androgens in the pros...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1349-7006.2010.01774.x

データ提供：米国国立医学図書館（NLM）

A New Era of Combined Androgen Blockade for Prostate Cancer: A Reassessment

Prostate cancer, a common health concern for men, can be treated effectively with androgen deprivation therapy. This research, like a group of explorers revisiting a forgotten map, re-examines the efficacy and safety of combined androgen blockade (CAB) for this disease.

More Effective Than Castration Alone? A Question of Balance

The study delves into the debate surrounding CAB, questioning whether it offers superior effectiveness compared to castration alone. This is like carefully analyzing an ancient map, trying to determine the best route to a hidden treasure.

Bicalutamide: A New Hope for CAB?

The authors highlight the potential of bicalutamide as a new antiandrogen for CAB, offering promising results in terms of overall survival and safety.

Dr. Camel's Conclusion

This research provides a valuable reassessment of combined androgen blockade for prostate cancer. While more research is needed, the promising results with bicalutamide offer a potential new approach to this disease.

Date :
  1. Date Completed 2011-01-18
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

21091846

DOI: Digital Object Identifier

10.1111/j.1349-7006.2010.01774.x

Related Literature

Article Analysis
・Effects of nilutamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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