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Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus.

Author: AzarN J, EstephanB, KoubeissiM Z, MayorC L, RashidS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intravenous lacosamide may be safe and efficacious as an add-on AED for the treatment of NCSE when standard therapy fails.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Lacosamide (LCM) is a novel antiepileptic drug (AED) recently approved as an adjunctive therapy in the treatment of partial seizures in adults. LCM is available in oral and intravenous formulations, has linear pharmacokinetics and a unique mechanism of action. THE AIM OF THIS STUDY: To ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1600-0404.2010.01430.x

データ提供：米国国立医学図書館（NLM）

Intravenous Lacosamide: A New Hope for Refractory NCSE

Nonconvulsive status epilepticus (NCSE), a severe neurological condition characterized by prolonged seizures without visible convulsions, can be challenging to treat. Lacosamide, a novel antiepileptic drug, has shown promise in treating various types of seizures, including NCSE. This study investigates the safety and efficacy of intravenous lacosamide in patients with refractory NCSE.

The researchers reviewed the cases of four patients with NCSE who had failed conventional therapy. They found that intravenous lacosamide successfully controlled seizures in all four patients, highlighting its potential as a treatment option for refractory NCSE.

Intravenous Lacosamide: A Potential Solution for Refractory NCSE

The study suggests that intravenous lacosamide could be a valuable treatment option for patients with NCSE who have not responded to conventional therapy. Lacosamide's efficacy in treating refractory NCSE offers a new avenue for managing this challenging neurological condition.

Hope for Patients with Refractory NCSE

This research provides hope for patients with refractory NCSE. Intravenous lacosamide's potential as a treatment option offers a new path to seizure control and improved quality of life for individuals struggling with this severe neurological condition.

Dr. Camel's Conclusion

This study, like a desert traveler discovering a hidden oasis, highlights the potential of intravenous lacosamide as a treatment option for refractory NCSE. Lacosamide's efficacy in controlling seizures in patients who have failed conventional therapy provides hope for improved outcomes and better seizure management.

Date :
  1. Date Completed 2011-04-26
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

21198444

DOI: Digital Object Identifier

10.1111/j.1600-0404.2010.01430.x

Related Literature

Article Analysis
・Side Effects of lacosamide injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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